| 货号 | MAB2924-SP |
| 别名 | Iboctadekin; IFN-gamma-inducing factor; IGIF; IGIFIL-1 gamma; IL-18MGC12320; IL-1F4; IL1F4iboctadekin; IL-1g; Interferon gamma-inducing factor; interleukin 18 (interferon-gamma-inducing factor); Interleukin-1 gamma; interleukin-18 | 全称 | Interleukin 18 |
| 反应种属 | Canine |
| 应用 | Western Blot(1 µg/mL) |
| 目标/特异性 | Detects canine IL‑18/IL‑1F4 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) IL-18, recombinant mouse (rm) IL-18, recombinant porcine IL-18, recombinant rat IL-18, recombinant rhesus macaque IL-18, rhIL‑36Ra, rhIL-1F7, rhIL-36 gamma, rhIL-1F10, rmIL-1ra, rmIL-36 gamma, or rmIL-36 alpha is observed. |
| 使用方法 | Western Blot: 1 µg/mL |
| 来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 3606 (Human); 16173 (Mouse); 29197 (Rat); 397057 (Porcine); 574151 (Primate) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | E. coli-derived recombinant canine IL‑18/IL‑1F4 Tyr37-Ser193 Accession # Q9XSR0 |
| 生物活性 | Canine |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | Interleukin 18, also known as interferon-gamma-inducing factor (IGIF) or IL-1 gamma, is an 18 kDa member of the IL-1 superfamily which shares biologic activities with IL‑12. IL-18 is expressed by liver cells, monocyte/macrophages, osteoblasts and keratinocytes. Mature canine IL-18 shares 73% sequence identity with human IL-18. Caspase-1 (IL-1 beta-converting enzyme) has been shown to process pro-IL-18 to active IL-18. Human IL-18 has been shown to enhance NK cell activity, induce the production of IFN-gamma and GM-CSF and inhibit the production of IL-10 by PBMCs. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
|