概述货号 | MAB232-SP |
别名 | AFGF; alpha; alpha-ECGF; beta-ECGF; ECGF; ECGFB; ECGF-betaAcidic fibroblast growth factor; endothelial cell growth factor, beta; FGF1; FGF-1; FGFABeta-endothelial cell growth factor; FGF-alpha; fibroblast growth factor 1 (acidic); GLIO703; HBGF1; HBGF-1; heparin-binding growth factor 1 |
全称 | Fibroblast Growth Factor acidic | 反应种属 | Human |
应用 | Western Blot(1 µg/mL)
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目标/特异性 | Detects rhFGF acidic in direct ELISAs and Western blots. Does not cross-react with any other family members tested.1 |
使用方法 | Western Blot: 1 µg/mL
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来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
产品组分 | |
性能供应商 | R&D Systems |
Entrez Gene IDs | 2246 (Human); 14164 (Mouse); 25317 (Rat); 281160 (Bovine) |
纯化方式 | Protein A or G purified from ascites |
免疫原 | E. coli-derived recombinant human FGF acidic |
内毒素水平 | <0.10 EU per 1 μg of the antibody by the LAL method. |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
背景 | FGF acidic, also known as FGF-1, ECGF, and HBGF-1, is a 17 kDa nonglycosylated member of the FGF family of mitogenic peptides. FGF acidic, which is produced by multiple cell types, stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis. Alternate splicing generates a truncated isoform of human FGF acidic that consists of the N-terminal 40% of the molecule and functions as a receptor antagonist. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 | - Adult Neurogenesis
- Cancer Biomarkers
- Developmental Factors Implicated in Neurodegeneration
- Diabetes
- EMT Induction
- FGF Family
- FGF Ligands
- Fibroblast Growth Factors and their Receptors
- Mini-review: Fibroblast Growth Factors (FGFs)
- Nutrition and Appetite
- Obesity
- Proliferation Bioassay NR6R 3T3 Cells
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