货号 | MAB2635-SP |
别名 | botv; DKFZp686C2342; EC 2.4.1.223; exostoses (multiple)-like 3; exostosin-like 3; EXTL1L; EXTL3; EXTR1BOTV; EXT-related protein 1; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Hereditary multiple exostoses gene isolog; KIAA0519; Multiple exostosis-like protein 3; Putative tumor suppressor protein EXTL3; reg receptor; REG; REGR; RPR |
反应种属 | Human |
应用 | Western Blot(1 µg/mL) Immunoprecipitation(25 µg/mL) |
目标/特异性 | Detects human Exostosin-like 3/EXTL3 in direct ELISAs and Western blots. |
使用方法 | Western Blot: 1 µg/mL Immunoprecipitation: 25 µg/mL |
来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 2137 (Human) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human Exostosin-like 3/EXTL3 Thr52-Ile919 Accession # O43909 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
背景 | EXTL3 is an ER-resident type II transmembrane protein belonging to theEXT family of tumor suppressor genes. EXT family members are glycosyltransferases that are involved in the synthesis of theglycosaminoglycan chains of heparan sulfate proteoglycans. EXTL3 wasalso reported to be a receptor for the REG protein, a pancreaticbeta-cell regeneration factor. The amino acid sequence of rhEXTL3 is98%, 97%, 88%, and 83% identical to that of dog, rat/mouse, Xenopus and zebrafish. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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