| 货号 | MAB609-SP |
| 别名 | CLMF2; IL12B; IL-12B; NKSF2 | 全称 | Interleukin 12/Interleukin 23 p40 |
| 反应种属 | Human |
| 应用 | ELISA Capture (Matched Antibody Pair)(2-8 µg/mL ) ELISA Detection (Matched Antibody Pair)(0.1-0.4 µg/mL ) ELISA Standard ( ) |
| 目标/特异性 | Detects human IL-12/IL-23 p40 in ELISAs. In ELISAs, this antibody shows less than 5% cross-reactivity with recombinant human (rh) IL‑12 (p35/p40 heterodimer) and rhIL-23 (p19/p40 heterodimer). No significant cross-reactivity or interference was observed with rhIL-1 alpha, rmIL-1 alpha, rhIL-1 beta, rmIL-1 beta, rhIL-1ra, rhIL-1 RI, rhIL-1 RII, rhIL-2, rhIL-2 R alpha, rhIL-3, rmIL-3, rhIL-4, rmIL-4, rhIL-4 R, rhIL-5, rmIL-5, rhIL-5 R beta, rhIL-6, rhIL-6 R, rmIL-6, rhIL-7, rmIL-7, rhIL-8, rhIL-9, rmIL-9, rhIL-10, rmIL-10, rhIL-11, rmIL-12, rmIL-12 p40, rhIL-13, or rmIL-13. |
| 使用方法 | ELISA Capture (Matched Antibody Pair): 2-8 µg/mL ELISA Detection (Matched Antibody Pair): 0.1-0.4 µg/mL ELISA Standard : |
| 来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 3593 (Human); 16160 (Mouse); 64546 (Rat); 403976 (Canine); 493741 (Feline) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Human rhinoviruses induce IL-35-producing Treg via induction of B7-H1 (CD274) and sialoadhesin (CD169) on DC. | |
| 纯化方式 | Protein A or G purified from ascites |
| 免疫原 | S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-12/IL-23 p40 free monomer Ile23-Ser328 Accession # P29460 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | Interleukin 12, also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a pleiotropic cytokine originally identified in the medium of activated human B lymphoblastoid cell lines. IL-12 is produced by macrophages and B lymphocytes and has multiple effects on T-cells and NK cells, including stimulation of cytotoxic activity, proliferation, and promotion of Th1 development as well as IFN-gamma and TNF production. IL-12 is a |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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