货号 | MAB2096-SP |
别名 | CD172 antigen-like family member B; CD172b antigen; CD172b; DKFZp686A05192; FLJ26614; signal-regulatory protein beta 1; signal-regulatory protein beta-1; SIRPB1; SIRP-beta-1 isoform 3; SIRP-BETA-1 | 全称 | Signal-regulatory Protein beta 1 |
反应种属 | Human |
应用 | Western Blot(1 µg/mL) Flow Cytometry(2.5 µg/106cells) |
目标/特异性 | Detects human SIRP beta 1/CD172b in direct ELISAs and Western blots. |
使用方法 | Western Blot: 1 µg/mL Flow Cytometry: 2.5 µg/106cells |
来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 10326 (Human) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human SIRP beta 1/CD172b Gly26-Ala369 (Arg53His and Ala363Pro) Accession # O00241.4 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
背景 | SIRP beta 1 is a type I transmembrane protein belonging to the SIRP familywithin the Ig superfamily. Members of this family are characterized byan extracellular region containing a V-set Ig domain containing aJ-like sequence and two C1-set Ig domains. Unlike SIRP alpha that hascytoplasmic ITIM domains, SIRP beta 1 possesses positively charged residuesthat allow association with ITAM motif containing adaptor molecules.SIRP beta 1 is expressed on cells of monocyte, macrophage or dendriticlineages. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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