Human PI 3-kinase p110 gamma MAb (Clone 304103) (25 UG)【科瑞奥博】

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Human PI 3-kinase p110 gamma MAb (Clone 304103) (25 UG)

货号： MAB2999-SP 基本售价： 1467.3 元规格： -

产品信息

概述
货号	MAB2999-SP
别名	1-phosphatidylinositol 3-kinase; EC 2.7.1; EC 2.7.1.153; p110-gamma; p120-PI3K; phosphatidylinositol 3 kinase gamma, p110 gamma; phosphatidylinositol 3-kinase catalytic 110-kD gamma; phosphatidylinositol 3-kinase, catalytic, gamma polypeptide; Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; phosphoinositide-3-kinase gamma catalytic subunit; phosphoinositide-3-kinase, catalytic, gamma polypeptide; PI3CG; PI3K; PI3K-gamma ; PI3Kgamma; PI3K-gamma; PI3-kinase subunit gamma; PIK3; PIK3CG; PtdIns-3-kinase subunit gamma; PtdIns-3-kinase subunit p110-gamma
全称	Protein Tyrosine Phosphatase 1G
反应种属	Human
应用	Western Blot(1 µg/mL)
目标/特异性	Detects endogenous human PI 3-Kinase p110 gamma in Western blots.
使用方法	Western Blot: 1 µg/mL
来源	Reconstitute at 0.5 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	5294 (Human); 30955 (Mouse); 298947 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Phosphoinositide 3-kinase mediated signaling in lobster olfactory receptor neurons. Authors: Corey EA, Bobkov Y, Pezier A, Ache BW J. Neurochem., 2010;113(2):341-50. Species: Lobster Sample Type: Cell Lysate Application: WB Nuclear factor-kappaB decoy oligodeoxynucleotides ameliorate impaired glucose tolerance and insulin resistance in mice with cecal ligation and puncture-induced sepsis. Authors: Matsuda N, Yamamoto S, Yokoo H, Tobe K, Hattori Y Crit. Care Med., 2009;37(10):2791-9. Species: Mouse Sample Type: Tissue Homogenates Application: WB
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	E. coli-derived recombinant human PI 3-Kinase p110 gamma Lys298-Leu467 Accession # P48736
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.5 mg/mL in sterile PBS.
背景	Class I phosphoinositide 3-kinases (PI 3-Kinases) are dual-specific lipid and protein kinases involved in numerous intracellular signaling pathways. Class IA PI 3‑Kinases (p110 alpha, beta and δ) are typically activated through receptor tyrosine kinase signaling, whereas p110 gamma, the single member of class IB, is activated by seven‑transmembrane G‑protein‑coupled receptors (GPCRs). While p110 alpha and beta are ubiquitiously expressed, expression of p110 gamma is mainly restricted to cells of the hematopoietic system.
运输条件	Blue Ice
存放说明	4℃
参考文献	Airway Inflammation and Remodeling Apoptosis Intracellular Kinases Chemokine Receptor Intracellular Signaling Common gamma Chain Receptor Family Diabetic Peripheral Neuropathy GDNF Family Intracellular Kinases Intracellular Kinases in the Akt Pathway Intracellular Signaling Molecules in Angiogenesis Neurotrophin/Trk Family Notch Pathway PDGF Family Signaling Molecules and Transcriptional Regulators of Tfh Cell Differentiation TNF Superfamily Regulators VEGF Family

参考图片

Detection of Human PI 3-Kinase p110 gamma by Western Blot. Western blot shows lysates of K562 human chronic myelogenous leukemia cell line and Raji human Burkitts lymphoma cell line. PVDF membrane was probed with 1 µg/mL of Human PI 3-Kinase p110 gamma Monoclonal Antibody (Catalog # MAB2999) followed by HRP-conjugated Anti-Rat IgG Secondary Antibody (Catalog # HAF005). A specific band was detected for PI 3-Kinase p110 gamma at approximately 110 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.