货号 | MAB17842-SP |
别名 | EC 3.4.24; EC 3.4.24.71; ECE; ECE-1; endothelin converting enzyme 1; endothelin-converting enzyme 1 | 全称 | Endothelin-converting Enzyme-1 |
反应种属 | Human |
应用 | Immunohistochemistry |
目标/特异性 | Detects human ECE-1 in direct ELISAs. |
使用方法 | Immunohistochemistry |
来源 | Sterile PBS to a final concentration of 0.5 mg/mL. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 1889 (Human) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human ECE-1 Gln90-Trp770 Accession # P42892 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Sterile PBS to a final concentration of 0.5 mg/mL. |
背景 | ECE-1 and -2 are zinc proteases of the neprilysin (NEP) family, which also includes PEX, XCE, DINE, Kell, and several NEP-like proteins. ECE-1 and -2 are type II transmembrane proteins with a short cytoplasmic tail and a large ectodomain. Several variants with alternatively spliced cytoplasmic tails exist that differ in their tissue distribution. ECE-1 and -2 cleave a variety of bioactive peptides including big endothelin-1. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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