Human/Mouse TOR MAb (Clone 303728) (25 UG)【科瑞奥博】

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Human/Mouse TOR MAb (Clone 303728) (25 UG)

货号： MAB1537-SP 基本售价： 1467.3 元规格： -

产品信息

概述
货号	MAB1537-SP
别名	EC 2.7.11.1; FK506 binding protein 12-rapamycin associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; FLJ44809; FRAP; FRAP1; FRAP1FKBP12-rapamycin complex-associated protein 1; FRAP2; Mammalian target of rapamycin; mechanistic target of rapamycin (serine/threonine kinase); Mechanistic target of rapamycin; MTOR; RAFT1; rapamycin and FKBP12 target 1; rapamycin associated protein FRAP2; Rapamycin target protein 1; RAPT1FKBP-rapamycin associated protein; serine/threonine-protein kinase mTOR
全称	Mammalian Target of Rapamycin
反应种属	Human/Mouse
应用	Immunocytochemistry(8-25 µg/mL)
目标/特异性	Detects human TOR in direct ELISAs.
使用方法	Immunocytochemistry: 8-25 µg/mL
来源	Reconstitute at 0.5 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	2475 (Human); 287871 (Rat)
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	E. coli-derived recombinant human TOR Phe1720-Ala2020 Accession # P42345
生物活性	Human, Mouse
标记	Unconjugated
溶解方法	Reconstitute at 0.5 mg/mL in sterile PBS.
背景	TOR, also known as FRAP1, is a member of the PI 3-kinase-related kinase (PIKK) family. It is the protein target of rapamycin, an anti-rejection drug used in transplantation and promising anti-cancer agent. TOR plays a crucial role in the control of cell growth and proliferation as a downstream target of the PI 3-kinase/Akt signal transduction pathway.
运输条件	Blue Ice
存放说明	4℃
参考文献	A Novel Pathway for TOR-independent Autophagy Regulation by Akt Apoptosis Intracellular Kinases Autophagy Chemokine Receptor Intracellular Signaling Growth Hormone/IGF-I Axis ICC / IHC Images: TOR Interactive Pathway: mTOR Signaling Intracellular Kinases Intracellular Kinases in the Akt Pathway Notch Pathway Parkinsons Disease Related Molecules Positive Regulators of the Jak/STAT Pathway Regulatory T Cells (Tregs) ROS and Stress Resistance

参考图片

TOR in MCF-7 Human Cell Line. TOR was detected in immersion fixed MCF-7 human breast cancer cell line using 10 µg/mL Human/Mouse TOR Monoclonal Antibody (Catalog # MAB1537) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.