| 货号 | MAB2786-SP |
| 别名 | C49A; FISP; IL10B; IL-24; interleukin 24; MDA-7; MDA7MOB5; melanocyte-associated Mda-7; melanoma differentiation association protein 7; Melanoma differentiation-associated gene 7 protein; MOB-5; ST16; ST16interleukin-24; suppression of tumorigenicity 16 (melanoma differentiation); Suppression of tumorigenicity 16 protein | 全称 | Interleukin 24 |
| 反应种属 | Mouse |
| 应用 | Western Blot(1 µg/mL) Immunocytochemistry(8-25 µg/mL) |
| 目标/特异性 | Detects mouse IL-24 in direct ELISAs and Western blots. No cross-reactivity with recombinant human IL-24 is observed. |
| 使用方法 | Western Blot: 1 µg/mL Immunocytochemistry: 8-25 µg/mL |
| 来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 11009 (Human); 93672 (Mouse); 170819 (Rat) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Dysregulation of suppressor of cytokine signaling 3 in keratinocytes causes skin inflammation mediated by interleukin-20 receptor-related cytokines. | |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | E. coli-derived recombinant mouse IL-24 Arg27-His181 Accession # NP_444325 |
| 生物活性 | Mouse |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | Mouse IL-24, also known as melanoma differentiation-associated gene 7(MDA-7) and Th2-specific cytokine FISP, is a 27 kDa secretedglycoprotein that is a member of the IL-10 family. It is synthesized asa precursor with a large pro-region that is removed to generate a155 aa mature protein. Mature mouse IL-24 shares 84% and 69% amino acididentity with rat and human IL-24, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
|
IL‑24 in Mouse Splenocytes. IL‑24 was detected in immersion fixed mouse splenocytes using Rat Anti-Mouse IL‑24 Monoclonal Antibody (Catalog # MAB2786) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Rat IgG Secondary Antibody (red; Catalog # NL013) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. View our protocol for Fluorescent ICC Staining of Non-adherent Cells. |
