Human/Mouse/Rat Akt2 MAb (Clone 302514) (25 UG)【科瑞奥博】

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Human/Mouse/Rat Akt2 MAb (Clone 302514) (25 UG)

货号： MAB2315-SP 基本售价： 1467.3 元规格： -

产品信息

概述
货号	MAB2315-SP
别名	EC 2.7.11; EC 2.7.11.1; Murine thymoma viral (v-akt) homolog-2; PKB beta; PKBB; PKBBETA; PRKBB; Protein kinase Akt-2; Protein kinase B beta; rac protein kinase beta; RAC-beta serine/threonine-protein kinase; RAC-beta; RAC-PK-beta; v-akt murine thymoma viral oncogene homolog 2
全称	v-Akt Murine Thymoma Viral Oncogene Homolog 2
反应种属	Human/Mouse/Rat
应用	Western Blot(2 µg/mL)
目标/特异性	Detects human, mouse, and rat Akt2. Detects human Akt2 in direct ELISAs and endogenous Akt2 in Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) Akt1 or rhAkt3 is observed.
使用方法	Western Blot: 2 µg/mL
来源	Reconstitute at 0.5 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	208 (Human); 11652 (Mouse); 29414 (Rat)
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Akt2 Asn2-Glu481 Accession # P31751
生物活性	Human, Mouse, Rat
标记	Unconjugated
溶解方法	Reconstitute at 0.5 mg/mL in sterile PBS.
背景	The serine/threonine kinase Akt, also known as protein kinase B (PKB), is a central regulator of such diverse cellular processes as glucose uptake, cell cycle progression, and apoptosis. In mammals, three highly homologous members define the Akt family: Akt1 (PKB alpha ), Akt2 (PKB beta ), and Akt3 (PKB gamma ). Akt2 is expressed predominantly in insulin target tissues such as liver, skeletal muscle, and fat.
运输条件	Blue Ice
存放说明	4℃
参考文献	A Novel Pathway for TOR-independent Autophagy Regulation by Akt Akt Modulates TGF-beta Activities Apoptosis Intracellular Kinases Chemokine Receptor Intracellular Signaling Common gamma Chain Receptor Family Diabetic Peripheral Neuropathy GDNF Family Human Phospho-MAPK Array Kit ICC / IHC Images: Akt2 Intracellular Kinases Intracellular Kinases in the Akt Pathway Intracellular Signaling Molecules in Angiogenesis Neurotrophin/Trk Family Notch Pathway PDGF Family TNF Superfamily Regulators VEGF Family

参考图片

Detection of Human/Mouse/Rat Akt2 by Western Blot. Western blot shows lysates of MDA-MB-468 human breast cancer cell line and Huh-7 human hepatoma cell line. PVDF membrane was probed with 2 µg/mL Mouse Anti-Human/Mouse/Rat Akt2 Monoclonal Antibody (Catalog # MAB2315) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). For additional reference, Recombinant Human Active Akt1 (Catalog # 1775-KS), recombinant human Akt2, and recombinant human Akt3 (2 ng/lane) were included. A specific band for Akt2 was detected at approximately 60 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 3.