| 货号 | MAB3338-SP |
| 别名 | CD294 antigen; CD294; Chemoattractant receptor-homologous molecule expressed on Th2 cells; CRTH2chemoattractant receptor homologous molecule expressed on T helper type 2 cells; DL1R; DP2; G protein-coupled receptor 44; GPR44; PGD2R; PTGDR2; putative G-protein coupled receptor 44 | 全称 | Chemoattractant Receptor-homologous Molecule Expressed on Th2 Cells |
| 反应种属 | Human |
| 应用 | Flow Cytometry(2.5 µg/106cells) |
| 目标/特异性 | Detects human CRTH‑2. Stains human CRTH-2-transfected cells but not parental cells. |
| 使用方法 | Flow Cytometry: 2.5 µg/106cells |
| 来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 11251 (Human); 14764 (Mouse); 309212 (Rat) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Novel association between vasoactive intestinal peptide and CRTH2 receptor in recruiting eosinophils: a possible biochemical mechanism for allergic eosinophilic inflammation of the airways. | |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | NS0 mouse myeloma cell line transfected with human CRTH-2 Met1-Ser395 Accession # Q9Y5Y4 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | CRTH-2, also known as GPR44, is a 7TM G protein-coupled receptor that isexpressed by activated Th2 cells and eosinophils. CRTH-2 bindsProstaglandin D2 and induces chemotaxis of these cells in allergic andinflammatory immune responses. Human and mouse CRTH-2 share 78% aminoacid sequence identity. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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