货号 | MAB2355-SP |
别名 | Cerebroglycan; GPC2 |
反应种属 | Mouse |
应用 | Western Blot(1 µg/mL) Immunohistochemistry(8-25 µg/mL) |
目标/特异性 | Detects mouse Glypican 2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with recombinant human GPC2, 3, 5, or 6 is observed. |
使用方法 | Western Blot: 1 µg/mL Immunohistochemistry: 8-25 µg/mL |
来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 221914 (Human); 71951 (Mouse) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse Glypican 2 Lys27-Leu554 Accession # Q8BKV1 |
内毒素水平 | <0.10 EU per 1 μg of the antibody by the LAL method. |
生物活性 | Mouse |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
背景 | The glypicans (GPC) constitute a family of glycosylphosphatidylinositol (GPI)-anchored, heparan sulfate proteoglycans. Six members of this family have been identified in mammals (GPC1-GPC6). All glypican core proteins contain an N-terminal signal peptide, a large globular cysteine-rich domain (CRD) with 14 invariant cysteine residues, a stalk-like region containing the heparan sulfate attachment sites, and a C-terminal GPI attachment site. Glypican 2, also known as cerebroglycan, binds Midkine and is primarily expressed in developing neuronal tissues. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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