Human LILRB4/CD85k/ILT3 MAb (Clone 293623) (25 UG)【科瑞奥博】

产品中心

当前位置：首页>产品中心

Human LILRB4/CD85k/ILT3 MAb (Clone 293623) (25 UG)

货号： MAB24251-SP 基本售价： 1467.3 元规格： -

产品信息

概述
货号	MAB24251-SP
别名	CD85 antigen-like family member K; CD85k antigen; CD85k; HM18; ILT3; ILT-3; ILT3CD85K; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains); LIR5; LIR5LILRB5; LIR-5subfamily B, member 4; member 4
全称	Leukocyte Immunoglobulin-like Receptor, Subfamily B (with TM and ITIM Domains), Member 4
反应种属	Human
应用	Western Blot(1 µg/mL) Flow Cytometry(0.25 µg/10⁶cells)
目标/特异性	Detects human LILRB4/CD85k/ILT3 in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with with recombinant human (rh) ILT5 is observed. No cross-reactivity with rhILT1, rhILT2, rhILT4, rhILT7, rhILT11, rhLIR-6 or rhLIR-8 is observed.
使用方法	Western Blot: 1 µg/mL Flow Cytometry: 0.25 µg/10⁶cells
来源	Reconstitute at 0.5 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	11006 (Human); 14728 (Mouse)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Identification of IDO-positive and IDO-negative human dendritic cells after activation by various proinflammatory stimuli. Authors: Von Bubnoff D, Scheler M, Wilms H, Fimmers R, Bieber T J. Immunol., 2011;186(12):6701-9. Species: Human Sample Type: Whole Cells Application: Flow The inhibitory Fc gamma IIb receptor dampens TLR4-mediated immune responses and is selectively up-regulated on dendritic cells from rheumatoid arthritis patients with quiescent disease. Authors: Wenink MH, Santegoets KC, Roelofs MF, Huijbens R, Koenen HJ, van Beek R, Joosten I, Meyer-Wentrup F, Mathsson L, Ronnelid J, Adema GJ, Bonvini E, Koenig S, van den Berg WB, van Riel PL, Radstake TR J. Immunol., 2009;183(7):4509-20. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Mouse myeloma cell line NS0-derived recombinant human LILRB4/CD85k/ILT3 Pro17-His257 Accession # ABM86208
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.5 mg/mL in sterile PBS.
背景	Immunoglobulin-Like Transcript 3 (ILT3), also known as Leukocyte Immunoglobulin-Like Receptor subfamily B member 4 (LILRB4) and Leukocyte Immunoglobulin-like Receptor 5 (LIR-5), is a type I membrane protein that functions as a receptor for class I MHC antigens. It contains cytoplasmic ITIM motifs and is involved in the down-regulation of immune responses.
运输条件	Blue Ice
存放说明	4℃
参考文献	Angiopoietins, Angiopoietin-like Proteins, and Receptors B Cell Activation Common Macrophage Markers Co-stimulatory and Co-inhibitory Molecules Dendritic Cell ITIM/ITAM Immunoreceptors Dendritic Cell Pathogen Recognition/Uptake Human CD Marker Products ITIM/ITAM Immunoreceptors and Related Molecules Monocyte Markers T Cell Antigen Recognition

参考图片

Detection of LILRB4/CD85k/ILT3 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human IL‑3 R alpha /CD123 PE‑conjugated Monoclonal Antibody (Catalog # FAB301P) and either (A) Mouse Anti-Human LILRB4/CD85k/ILT3 Monoclonal Antibody (Catalog # MAB24251) or (B) Mouse IgG_2A Isotype Control (Catalog # MAB003) followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B).