货号 | MAB1996-SP |
别名 | PAP1 | 全称 | Regenerating Islet-derived IIIb |
反应种属 | Rat |
应用 | Western Blot(1 µg/mL) Immunohistochemistry(8-25 µg/mL) |
目标/特异性 | Detects rat Reg3B in direct ELISAs and Western blots. Does not cross-react with recombinant mouse Reg1A, 1B, 2A, recombinant rat Reg3, or recombinant human Reg4. |
使用方法 | Western Blot: 1 µg/mL Immunohistochemistry: 8-25 µg/mL |
来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 18489 (Mouse); 24618 (Rat) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | E. coli-derived recombinant rat Reg3B Glu27-Gly175 Accession # P25031 |
生物活性 | Rat |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
背景 | Reg3B, also named Pancreatitis-Associated Protein (PAP) and peptide 23, belongs to the Regenerating gene family (Reg), within the superfamily of C-type lectins. It has been classified as a member of the type III subclass of the Reg family. Reg3B has anti-apoptotic effects on pancreatic acinar cells and is a novel motor and sensory neuron survival factor. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Reg3B in Rat Pancreas. Reg3B was detected in perfusion fixed frozen sections of rat pancreas using Mouse Anti-Rat Reg3B Monoclonal Antibody (Catalog # MAB1996) at 25 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). Specific labeling was localized to the cytoplasm of exocrine cells. View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections. |