Human S1P5/EDG-8 MAb (Clone 282503) (25 UG)【科瑞奥博】

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Human S1P5/EDG-8 MAb (Clone 282503) (25 UG)

货号： MAB3964-SP 基本售价： 1467.3 元规格： -

产品信息

概述
货号	MAB3964-SP
别名	EDG8; Edg-8; EDG8S1P receptor Edg-8; Endothelial differentiation G-protein-coupled receptor 8; endothelial differentiation, sphingolipid G-protein-coupled receptor, 8; LPB4; S1P receptor 5; S1P5; S1PR5; sphingosine 1-phosphate receptor 5; sphingosine 1-phosphate receptor EDG8; Sphingosine 1-phosphate receptor Edg-8; sphingosine-1-phosphate receptor 5; SPPR-1; SPPR-2
全称	Endothelial Differentiation Gene 8
反应种属	Human
应用	Flow Cytometry(0.25 µL/10⁶cells)
目标/特异性	Detects human S1P₅/EDG‑8. Stains human S1P₅/EDG‑8 transfectants but not irrelevant transfectants.
使用方法	Flow Cytometry: 0.25 µL/10⁶cells
来源	Reconstitute at 0.5 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	53637 (Human); 94226 (Mouse); 60399 (Rat)
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	BaF3 mouse pro-B cell line transfected with human S1P₅/EDG‑8 Met1-Asp398 Accession # Q9H228
内毒素水平	<0.10 EU per 1 μg of the antibody by the LAL method.
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.5 mg/mL in sterile PBS.
背景	S1P₅ is also known as EDG-8 and nerve growth factor-related G-protein-coupled receptor-1 (NRG-1). S1P₅ is a 398 amino acid (aa) seven-transmembrane receptor putative glycoprotein that binds the lysolipid phosphoric acid mediator, sphingosine 1-phosphate. Extracellular portions of human S1P₅ show 96% and 97% aa identity with mouse and rat S1P₅, respectively. Isoform 1 is expressed at a low level in peripheral tissues. Isoform 2 has an alternate C-terminal that is 88 aa shorter and is expressed mainly in brain, spleen, and PBMC. S1P₅ is upregulated in large granular lymphocytic leukemias.
运输条件	Blue Ice
存放说明	4℃
参考文献	Bioactive Lipid G Protein-Coupled Receptors Endothelial Cell Differentiation Markers Endothelial Cell Markers Endothelial Cell Markers and Adhesion Molecules in Angiogenesis Endothelial Progenitor and Endothelial Cell Markers Steroid Hormones and Bioactive Lipids

参考图片

Detection of S1P₅/EDG‑8 in HEK293 Human Cell Line Transfected with Human S1P₅/EDG‑8 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with human S1P₅/EDG‑8 and eGFP were stained with either (A) Mouse Anti-Human S1P₅/EDG‑8 Monoclonal Antibody (Catalog # MAB3964) or (B) Mouse IgG_2B Flow Cytometry Isotype Control (Catalog # MAB0041). View our protocol for Staining Membrane-associated Proteins.