Mouse YM1/Chitinase 3-like 3 MAb (Clone 281926) (25 UG)【科瑞奥博】

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Mouse YM1/Chitinase 3-like 3 MAb (Clone 281926) (25 UG)

货号： MAB2446-SP 基本售价： 1467.3 元规格： -

产品信息

概述
货号	MAB2446-SP
别名	AI505981; CHI3L3; Chitinase 3-like 3; ECF-L; Ym1
反应种属	Mouse
应用	Western Blot(0.5 µg/mL)
目标/特异性	Detects mouse YM1/Chitinase 3-like in direct ELISAs and Western blots.
使用方法	Western Blot: 0.5 µg/mL
来源	Reconstitute at 0.5 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	12655 (Mouse)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Protective immunity against pulmonary cryptococcosis is associated with STAT1-mediated classical macrophage activation. Authors: Hardison S, Herrera G, Young M, Hole C, Wozniak K, Wormley F J Immunol, 2012;189(8):4060-8. Species: Mouse Sample Type: Whole Tissue Application: IHC Frozen Central nervous system fibrosis is associated with fibrocyte-like infiltrates. Authors: Aldrich A, Kielian T Am. J. Pathol., 2011;179(6):2952-62. Species: Mouse Sample Type: Cell Lysates Application: WB p47phox deficiency induces macrophage dysfunction resulting in progressive crystalline macrophage pneumonia. Authors: Liu Q, Cheng LI, Yi L, Zhu N, Wood A, Changpriroa CM, Ward JM, Jackson SH Am. J. Pathol., 2009;174(1):153-63. Species: Mouse Sample Type: Cell Lysates Application: WB
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Mouse myeloma cell line NS0-derived recombinant mouse YM1/Chitinase 3-like Tyr22-Tyr398 Accession # O35744
生物活性	Mouse
标记	Unconjugated
溶解方法	Reconstitute at 0.5 mg/mL in sterile PBS.
背景	Eosinophil Chemotactic Factor L (ECF-L), also known as YM1, is a secreted lectin that binds heparin and G1cN oligomers. It is produced primarily by macrophages during inflammation. ECF-L shares homology with chitinase family proteins but lacks enzymatic activity.
运输条件	Blue Ice
存放说明	4℃
参考文献	Airway Inflammation and Remodeling Eosinophils Extracellular Matrix Molecules Glycobiology-related Enzymes Inflammatory Mediators Lysosomal Enzymes Macrophage Activation Markers Neuroinflammation

参考图片

Detection of Mouse YM1/Chitinase 3-like 3 by Western Blot. Western blot shows lysates of mouse bone marrow. PVDF membrane was probed with 0.5 µg/mL of Rat Anti-Mouse YM1/Chitinase 3-like 3 Monoclonal Antibody (Catalog # MAB2446) followed by HRP-conjugated Anti-Rat IgG Secondary Antibody (Catalog # HAF005). A specific band was detected for YM1/Chitinase 3-like 3 at approximately 45 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.