| 货号 | MAB26881-SP |
| 别名 | 3F8 CSPG ; HPTPZ; phosphacan; protein tyrosine phosphatase, receptor-type, Z polypeptide 1; PTP18; PTPRZ; PTPRZ1; PTPZ; receptor-type, zeta polypeptide 1; RPTPB; RPTPbeta | 全称 | Protein Tyrosine Phosphatase beta/zeta |
| 反应种属 | Human |
| 应用 | Immunohistochemistry(8-25 µg/mL) |
| 目标/特异性 | Detects human PTP beta / zeta /PTPRZ in direct ELISAs. |
| 使用方法 | Immunohistochemistry: 8-25 µg/mL |
| 来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 5803 (Human) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth | |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | E. coli-derived recombinant human PTP beta / zeta /PTPRZ Gly302-Asn754 Accession # P23471 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | PTPRZ, also known as Protein tyrosine phosphatase beta/zeta (PTP beta / zeta ), is a member of the receptor-type protein-tyrosine phosphatase family. This phosphatase is involved in the regulation of specific developmental processes in the central nervous system. A protein of 2,307 amino acids, PTPRZ is membrane-spanning with two cytoplasmic protein tyrosine phosphatase domains and an extracellular domain. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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PTP beta / zeta /PTPRZ in Human Brain. PTP beta / zeta /PTPRZ was detected in immersion fixed paraffin-embedded sections of human brain (cortex) using Rat Anti-Human PTP beta / zeta /PTPRZ Monoclonal Antibody (Catalog # MAB26881) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Rat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS017) and counterstained with hematoxylin (blue). Specific staining was localized to neuronal cell bodies. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections. |
