货号 | MAB2688-SP |
别名 | 3F8 CSPG ; HPTPZ; phosphacan; protein tyrosine phosphatase, receptor-type, Z polypeptide 1; PTP18; PTPRZ; PTPRZ1; PTPZ; receptor-type, zeta polypeptide 1; RPTPB; RPTPbeta | 全称 | Protein Tyrosine Phosphatase beta/zeta |
反应种属 | Human |
应用 | Western Blot(1 µg/mL) |
目标/特异性 | Detects human PTP beta / zeta /PTPRZ in Western blots. |
使用方法 | Western Blot: 1 µg/mL |
来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 5803 (Human) |
应用文献 | |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Midkine enhances soft-tissue sarcoma growth: a possible novel therapeutic target. | |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | E. coli-derived recombinant human PTP beta / zeta /PTPRZ Gly302-Asn754 Accession # P23471 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
背景 | Protein tyrosine phosphatase beta/zeta (PTP beta / zeta ), also known as PTPRZ, is a member of the receptor-type protein-tyrosine phosphatase family. This phosphatase is involved in the regulation of specific developmental processes in the central nervous system. A protein of 2,307 amino acids, PTPRZ is membrane-spanning with two cytoplasmic protein tyrosine phosphatase domains and an extracellular domain. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of Human PTP beta / zeta /PTPRZ by Western Blot. Western blot shows lysates of Jurkat human acute T cell leukemia cell line. PVDF membrane was probed with 1 µg/mL of Rat Anti-Human PTP beta / zeta /PTPRZ Monoclonal Antibody (Catalog # MAB2688) followed by HRP-conjugated Anti-Rat IgG Secondary Antibody (Catalog # HAF005). A specific band was detected for PTP beta / zeta /PTPRZ at approximately 250 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1. |