Human HTRA1/PRSS11 MAb (Clone 275615) (25 UG)【科瑞奥博】

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Human HTRA1/PRSS11 MAb (Clone 275615) (25 UG)

货号： MAB2916-SP 基本售价： 1467.3 元规格： -

产品信息

概述
货号	MAB2916-SP
别名	ARMD7; EC 3.4.21; EC 3.4.21.108; High-temperature requirement A serine peptidase 1; HtrA serine peptidase 1; IGFBP5-protease; L56; ORF480; PRSS11; Serine protease 11; serine, 11 (IGF binding)
全称	High Temperature Requirement Protein-1
反应种属	Human
应用	Western Blot(1 µg/mL) Immunoprecipitation(25 µg/mL)
目标/特异性	Detects human HTRA1/PRSS11 in direct ELISAs and Western blots.
使用方法	Western Blot: 1 µg/mL Immunoprecipitation: 25 µg/mL
来源	Reconstitute at 0.5 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	5654 (Human)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. HTRA1 promoter variant differentiates polypoidal choroidal vasculopathy from exudative age-related macular degeneration Authors: Tsz Kin Ng Sci Rep, 2016;6(0):28639. Species: Human Sample Type: tissue lysates Application: WB Protoporphyrins enhance oligomerization and enzymatic activity of HtrA1 serine protease. Authors: Jo, Hakryul, Patterson, Victoria, Stoessel, Sean, Kuan, Chia-Yi, Hoh, Josephin PLoS ONE, 2014;9(12):e115362. Species: Human Sample Type: Cell Culture Supernates Application: WB Down-Regulation of HtrA1 Activates the Epithelial-Mesenchymal Transition and ATM DNA Damage Response Pathways. Authors: Wang N, Eckert KA, Zomorrodi AR PLoS ONE, 2012;7(6):e39446. Species: Human Sample Type: Cell Lysates Application: WB Matrix remodeling as stem cell recruitment event: a novel in vitro model for homing of human bone marrow stromal cells to the site of injury shows crucial role of extracellular collagen matrix. Authors: Mauney J, Olsen BR, Volloch V Matrix Biol., 2010;29(8):657-63. Species: Human Sample Type: Cell Lysates Application: IP
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Mouse myeloma cell line NS0-derived recombinant human HTRA1/PRSS11 Gln23-Pro480 Accession # Q92743
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.5 mg/mL in sterile PBS.
背景	HTRA1 is a serine protease encoded by the PRSS11 gene and is expressedin many tissues. HTRA1 regulates the availability of IGFs by cleavingIGFBPs.
运输条件	Blue Ice
存放说明	4℃
参考文献	Serine Proteases and Regulators

参考图片

Detection of Human HTRA1/PRSS11 by Western Blot. Western blot shows lysates of human placenta tissue. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human HTRA1/PRSS11 Monoclonal Antibody (Catalog # MAB2916) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for HTRA1/PRSS11 at approximately 51 kDa (as indicated). This experiment was conducted under non-reducing conditions and using Immunoblot Buffer Group 1.