| 货号 | MAB2458-SP |
| 别名 | RGM domain family member A; RGM domain family, member A; RGMrepulsive guidance molecule A | 全称 | Repulsive Guidance Molecule A |
| 反应种属 | Human/Mouse |
| 应用 | Western Blot(1 µg/mL) |
| 目标/特异性 | Detects mouse RGM-A in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross‑reactivity with recombinant human RGM-A and recombinant chicken RGM is observed. In Western blots, approximately 25% cross-reactivity with recombinant mouse RGM-C is observed. |
| 使用方法 | Western Blot: 1 µg/mL |
| 来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 56963 (Human); 244058 (Mouse) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Repulsive guidance molecule-A (RGM-A) inhibits leukocyte migration and mitigates inflammation. | |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse RGM-A Cys48-Gly421 Accession # Q6PCX7 |
| 生物活性 | Human, Mouse, Chicken |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | RGM-A is the founding member of the RGM family of glycosylphosphatidylinositol (GPI)- anchored axon guidance proteins. It is a disulfide-linked dimer of the N‑terminal and C-terminal RGD-containing segments. RGM-A binds with high affinity to Neogenin. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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