Human PI 3-Kinase p110 beta MAb (Clone 269020) (25 UG)【科瑞奥博】

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Human PI 3-Kinase p110 beta MAb (Clone 269020) (25 UG)

货号： MAB2686-SP 基本售价： 1467.3 元规格： -

产品信息

概述
货号	MAB2686-SP
别名	P110BETA; PI3K; PI3KBETA; PIK3C1; PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; PIK3CB
全称	Protein Tyrosine Phosphatase 1B
反应种属	Human
应用	Western Blot(1 µg/mL)
目标/特异性	Detects endogenous human PI 3-kinase p110 beta in Western blots.
使用方法	Western Blot: 1 µg/mL
来源	Reconstitute at 0.5 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	5291 (Human)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Nuclear factor-kappaB decoy oligodeoxynucleotides ameliorate impaired glucose tolerance and insulin resistance in mice with cecal ligation and puncture-induced sepsis. Authors: Matsuda N, Yamamoto S, Yokoo H, Tobe K, Hattori Y Crit. Care Med., 2009;37(10):2791-9. Species: Mouse Sample Type: Tissue Homogenates Application: WB
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	E. coli-derived recombinant human PI 3-Kinase p110 beta Met152-Val349 Accession # P42338
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.5 mg/mL in sterile PBS.
背景	Class IA phosphoinositide 3-kinases (PI 3-kinases) are a family of p85/p110 heterodimeric lipid kinases that function as signal transducers downstream of growth factor receptors, mainly receptor tyrosine kinases. Mammals express three class IA catalytic subunits: p110 alpha, p110 beta, and p110δ. Reports suggest that the p110 beta subunit may have special importance in promoting cell proliferation.
运输条件	Blue Ice
存放说明	4℃
参考文献	Airway Inflammation and Remodeling Apoptosis Intracellular Kinases Chemokine Receptor Intracellular Signaling Common gamma Chain Receptor Family Diabetic Peripheral Neuropathy Epithelial Cell Polarity GDNF Family Intracellular Kinases Intracellular Kinases in the Akt Pathway Intracellular Signaling Molecules in Angiogenesis Neurotrophin/Trk Family Notch Pathway PDGF Family Signaling Molecules and Transcriptional Regulators of Tfh Cell Differentiation TNF Superfamily Regulators VEGF Family

参考图片

Detection of Human PI 3-Kinase p110 beta by Western Blot. Western blot shows lysates of A431 human epithelial carcinoma cell line and Jurkat human acute T cell leukemia cell line. PVDF membrane was probed with 1 µg/mL of Human PI 3‑Kinase p110 beta Monoclonal Antibody (Catalog # MAB2686) followed by HRP‑conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for PI 3‑Kinase p110 beta at approximately 110 kDa (as indicated). This experiment was conducted using Immunoblot Buffer Group 1.