| 货号 | MAB2394-SP |
| 别名 | dJ238O23.3; GLTL1825; PRO3438; TLT-1; TLT1MGC119173; trem-like transcript 1 protein; triggering receptor expressed on myeloid cells-like 1; Triggering receptor expressed on myeloid cells-like protein 1 | 全称 | Triggering Receptor Expressed on Myeloid Cells-like 1 |
| 反应种属 | Human |
| 应用 | Western Blot(1 µg/mL) Flow Cytometry(0.25 µg/106cells) |
| 目标/特异性 | Detects human TREML1/TLT‑1 in direct ELISAs and Western blots. In direct ELISAs, no cross‑reactivity with recombinant mouse TREML1 or recombinant human TREML2 is observed. |
| 使用方法 | Western Blot: 1 µg/mL Flow Cytometry: 0.25 µg/106cells |
| 来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 340205 (Human); 71326 (Mouse) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human TREML1/TLT‑1 Gln16-Ser160 Accession # Q86YW5 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | TREML1 is an inhibitory type I transmembrane protein that has twocytoplasmic ITIMs (Immunoreceptor Tyrosine-based Inhibition Motif). Asplice variant lacking ITIMs in its cytoplasmic domain also exists.TREML1 is found only in platelets and megakaryocytes. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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Detection of TREML1/TLT‑1 in Human Platelets by Flow Cytometry. Human peripheral blood platelets were stained with Mouse Anti-Human Integrin alpha 2b/CD41 PE‑conjugated Monoclonal Antibody (Catalog # FAB7616P) and either (A) Rat Anti-Human TREML1/TLT‑1 Monoclonal Antibody (Catalog # MAB2394) or (B) Rat IgG2B Isotype Control (Catalog # MAB0061) followed by Allophycocyanin-conjugated Anti-Rat IgG Secondary Antibody (Catalog # F0113). View our protocol for Staining Membrane-associated Proteins. |
