Mouse TLR4 MAb (Clone 267518) (25 UG)【科瑞奥博】

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Mouse TLR4 MAb (Clone 267518) (25 UG)

货号： MAB2759-SP 基本售价： 1467.3 元规格： -

产品信息

概述
货号	MAB2759-SP
别名	ARMD10; CD284 antigen; CD284; hTollhomolog of Drosophila toll; TOLL; toll-like receptor 4
全称	Toll-like Receptor 4
反应种属	Mouse
应用	Flow Cytometry(2.5 µg/10⁶cells) Immunocytochemistry(8-25 µg/mL)
目标/特异性	Detects mouse TLR4 in direct ELISAs. In direct ELISAs, does not cross-react with recombinant mouse TLR1, 2, 3, 6, or recombinant human TLR4.
使用方法	Flow Cytometry: 2.5 µg/10⁶cells Immunocytochemistry: 8-25 µg/mL
来源	Reconstitute at 0.5 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	7099 (Human); 21898 (Mouse); 29260 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Adjuvant effect of killed Propionibacterium acnes on mouse peritoneal B-1 lymphocytes and their early phagocyte differentiation. Authors: Mussalem JS, Squaiella-Baptistao CC, Teixeira D, Yendo TM, Thies FG, Popi AF, Mariano M, Longo-Maugeri I PLoS ONE, 2012;7(3):e33955. Species: Mouse Sample Type: Whole Cells Application: Flow Toll-like receptor 4 regulates early endothelial activation during ischemic acute kidney injury. Authors: Chen J, John R, Richardson JA, Shelton JM, Zhou XJ, Wang Y, Wu QQ, Hartono JR, Winterberg PD, Lu CY Kidney Int., 2011;79(3):288-99. Species: Mouse Sample Type: Whole Tissue Application: IHC Frozen Hemorrhagic shock augments lung endothelial cell activation: role of temporal alterations of TLR4 and TLR2. Authors: Li Y, Xiang M, Yuan Y, Xiao G, Zhang J, Jiang Y, Vodovotz Y, Billiar TR, Wilson MA, Fan J Am. J. Physiol. Regul. Integr. Comp. Physiol., 2009;297(6):R1670-80. Species: Mouse Sample Type: Tissue Homogenates Application: WB
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Mouse myeloma cell line NS0-derived recombinant mouse TLR4 Asn26-Lys629 Accession # Q9QUK6
生物活性	Mouse
标记	Unconjugated
溶解方法	Reconstitute at 0.5 mg/mL in sterile PBS.
背景	TLR4 belongs to the IL-1 receptor/Toll-like receptor superfamily. It is expressed in placenta and peripheral blood leukocytes. TLR4 is the pattern recognition receptor for LPS.
运输条件	Blue Ice
存放说明	4℃
参考文献	B Cell Markers BIObrief: Pattern Recognition Receptors & the Innate Immune Response Common Macrophage Markers Diabetes Human CD Marker Products ICC / IHC Images: TLR4 IL-1 Family Infectious Diseases Inflammatory Mediators Innate Immunity and the Toll-like Receptor Family Interactive Pathway: Inflammasome Activation Pathways Interactive Pathway: Toll-Like receptor Signaling Pathways Mini-review: The Toll-like Receptor Family Neuroinflammation NFkB Pathway NOD-like Receptors and the Inflammasome Obesity Parturition & Surfactant Protein A Pattern Recognition Receptors Regulatory T Cells (Tregs) T Cell Antigen Recognition TLR4: Contributing to Metabolic Syndrome in Multiple Tissues Toll-Like Receptors

参考图片

TLR4 in RAW 264.7 Mouse Monocyte/Macrophage Cell Line. TLR4 was detected in immersion fixed RAW 264.7 mouse monocyte/
macrophage cell line using Rat Anti-Mouse TLR4 Monoclonal Antibody (Catalog # MAB2759) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the
NorthernLights™ 557-conjugated Anti-Rat IgG Secondary Antibody (red; Catalog # NL013) and counterstained with DAPI(blue). Specific staining was localized to the cell surface. View our protocol for Fluorescent ICC Staining of Cells on Coverslips.