Human NKX2.5 MAb (Clone 259416) (25 UG)【科瑞奥博】

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Human NKX2.5 MAb (Clone 259416) (25 UG)

货号： MAB2444-SP 基本售价： 1467.3 元规格： -

产品信息

概述
货号	MAB2444-SP
别名	cardiac-specific homeo box; cardiac-specific homeobox 1; Cardiac-specific homeobox; CHNG5; CSX1; CSXFLJ97195; FLJ52202; FLJ99536; Homeobox protein CSX; Homeobox protein NK-2 homolog E; homeobox protein Nkx-2.5; NK2 transcription factor related, locus 5 (Drosophila); NKX2.5FLJ97166; NKX2-5; NKX2E; NKX2EFLJ97197; NKX4-1; tinman paralog
全称	NK2 Homeobox 5
反应种属	Human
应用	Immunohistochemistry(8-25 µg/mL)
目标/特异性	Detects human NKX-2.5 in direct ELISAs.
使用方法	Immunohistochemistry: 8-25 µg/mL
来源	Reconstitute at 0.5 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	1482 (Human)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Essential and unexpected role of Yin Yang 1 to promote mesodermal cardiac differentiation. Authors: Gregoire S, Karra R, Passer D, Deutsch M, Krane M, Feistritzer R, Sturzu A, Domian I, Saga Y, Wu S Circ Res, 2013;112(6):900-10. Species: Mouse Sample Type: Embryo Application: IHC OCT-embedded Dedifferentiated fat cells convert to cardiomyocyte phenotype and repair infarcted cardiac tissue in rats. Authors: Jumabay M, Matsumoto T, Yokoyama S, Kano K, Kusumi Y, Masuko T, Mitsumata M, Saito S, Hirayama A, Mugishima H, Fukuda N J. Mol. Cell. Cardiol., 2009;47(5):565-75. Species: Rat Sample Type: Whole Cells Application: ICC
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	E. coli-derived recombinant human NKX2.5 Gln24-Arg137 Accession # P52952
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.5 mg/mL in sterile PBS.
背景	NKX2.5, also called NKX-2E or Csx (Cardiac specific homeobox protein), is a transcriptional activator. Its expression is essential for normal cardiovascular development. During embryonic development, NKX2.5 is also expressed in the foregut, thyroid, spleen, and stomach, while in the adult expression is predominantly restricted to the heart.
运输条件	Blue Ice
存放说明	4℃
参考文献	Cardiac Stem Cell Markers Homeodomain (Hox) Transcription Factors ICC / IHC Images: NKX2.5 Transcription Factors and Regulators Transcription Factors in the Akt Pathway

参考图片

NKX2.5 in Human Heart. NKX2.5 was detected in immersion fixed paraffin-embedded sections of human heart using Mouse Anti-Human NKX2.5 Monoclonal Antibody (Catalog # MAB2444) at 25 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). Lower panel shows a lack of labeling if primary antibodies are omitted and tissue is stained only with secondary antibody followed by incubation with detection reagents. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.