| 货号 | MAB2260-SP |
| 别名 | BMP-2; BMP-2A; BMP2ABone morphogenetic protein 2A; bone morphogenetic protein 2 | 全称 | Bone Morphogenetic Protein 2 |
| 反应种属 | Human |
| 应用 | Western Blot(1 µg/mL) Immunohistochemistry(8-25 µg/mL) |
| 目标/特异性 | Detects the pro region of the human BMP-2 precursor in direct ELISAs and Western blots. This antibody does not recognize mature recombinant human BMP‑2. |
| 使用方法 | Western Blot: 1 µg/mL Immunohistochemistry: 8-25 µg/mL |
| 来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 650 (Human); 12156 (Mouse); 29373 (Rat) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Targeting of bone morphogenetic protein growth factor complexes to fibrillin. | |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human BMP‑2 Ala22-Lys281 (Arg245Ser, Arg279Ser) Accession # P12643 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | BMP-2, a member of the transforming growth factor beta (TGF-beta )superfamily, is synthesized as an inactive precursor protein. TheN-terminal pro region is removed via proteolytic cleavage to liberate afree 114 amino acid C-terminal fragment that forms a disulfide-linkedactive BMP-2 homodimer. BMP-2 modulates growth and differentiation ofmany cell types through its interaction with heterodimeric receptorscomposed of BMPR-II complexed with BMPR-IA or -IB. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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