| 货号 | MAB2086-SP |
| 别名 | 67kD); EC 4.1.1; FLJ45882; GAD25; GAD67; glutamate decarboxylase 1 (brain, 67kDa); Glutamate decarboxylase 67 kDa isoform | 全称 | Glutamate Decarboxylase 1 (Brain, 67kDa) |
| 反应种属 | Human |
| 应用 | Western Blot(1 µg/mL) Immunocytochemistry(8-25 µg/mL) |
| 目标/特异性 | Detects human GAD1/GAD67 in direct ELISAs and Western blots. |
| 使用方法 | Western Blot: 1 µg/mL Immunocytochemistry: 8-25 µg/mL |
| 来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 2571 (Human) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | E. coli-derived recombinant human GAD1/GAD67 Ala2-Asn97 Accession # Q99259 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | GAD1, also known as GAD67, is the enzyme responsible for the conversion of glutamic acid to gamma-aminobutyric acid (GABA), the major inhibitory transmitter in higher brain regions and putative paracrine hormone in pancreatic islets. GAD occurs as two molecular forms, 65 kDa and 67 kDa, that are encoded by separate genes and share 65% amino acid identity. GAD1 is highly conserved and is expressed in the CNS, pancreatic islet cells, testis, oviduct and ovary (1). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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