| 货号 | MAB1919-SP |
| 别名 | C9orf2; H7365member 1; Tomoregulin-1; TR-1; Transmembrane protein with EGF-like and one follistatin-like domain; transmembrane protein with EGF-like and two follistatin-like domains 1 | 全称 | Transmembrane Protein with EFG-like and two Follistatin-like Domains |
| 反应种属 | Human |
| 应用 | Western Blot(1 µg/mL) |
| 目标/特异性 | Detects human TMEFF1/Tomoregulin‑1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse TMEFF1 or recombinant human TMEFF2 is observed. |
| 使用方法 | Western Blot: 1 µg/mL |
| 来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 8577 (Human); 230157 (Mouse) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Gene expression profiling and real-time PCR analyses identify novel potential cancer-testis antigens in multiple myeloma. | |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human TMEFF1/Tomoregulin‑1 Ser40-Thr328 Accession # Q8IYR6 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | TMEFF1 (Transmembrane protein with EGF-like and two Follistatin-like domains 1), also known as tomoregulin 1 is a type I transmembraneglycoprotein that contains two follistatin modules and an EGF domain inits extracellular domain, a transmembrane domain and a shortcytoplasmic tail. The extracellular domain can be released as a solubleprotein. TMEFF1 selectively regulates nodal but not activin signalingthrough direct binding to the nodal co-receptor, Cripto. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
|