货号 | MAB2815-SP |
别名 | CC chemokine receptor 10; C-C chemokine receptor type 10; C-C CKR-10; CC-CKR-10; CCR10; CCR-10; chemokine (C-C motif) receptor 10; G protein-coupled receptor 2; GPR2; GPR2G-protein coupled receptor 2 |
反应种属 | Mouse |
应用 | Flow Cytometry(0.25 µg/106cells) |
目标/特异性 | Detects mouse CCR10. Stains mouse CCR10-transfected cells but not irrelevant transfectants. |
使用方法 | Flow Cytometry: 0.25 µg/106cells |
来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 2826 (Human); 12777 (Mouse); 363682 (Rat) |
应用文献 | |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells. | |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | C6 rat glioma cell line transfected with mouse CCR10 Met1-Asn362 Accession # NP_031747 |
内毒素水平 | <0.10 EU per 1 μg of the antibody by the LAL method. |
生物活性 | Mouse |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
背景 | CCR10 is a G protein-linked seven transmembrane domain protein expressed by T cells and B cell subsets that functions as a receptor for CCL27. CCR10 mediates lymphocyte migration to the skin and mucosa, and its expression correlates with the metastatic capacity of melanomas. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of CCR10 in HEK293 Human Cell Line Transfected with Mouse CCR10 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with mouse CCR10 and eGFP was stained with either (A) Rat Anti-Mouse CCR10 Monoclonal Antibody (Catalog # MAB2815) or (B) Rat IgG2B Isotype Control (Catalog # MAB0061) followed by Allophycocyanin-conjugated Anti-Rat IgG Secondary Antibody (Catalog # F0113). |