Human SOX17 MAb (Clone 245013) (25 UG)【科瑞奥博】

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Human SOX17 MAb (Clone 245013) (25 UG)

货号： MAB1924-SP 基本售价： 1467.3 元规格： -

产品信息

概述
货号	MAB1924-SP
别名	FLJ22252; SRY (sex determining region Y)-box 17; SRY-related HMG-box transcription factor SOX17; transcription factor SOX-17; VUR3
全称	Transcription Factor SOX17
反应种属	Human
应用	Immunocytochemistry(8-25 µg/mL)
目标/特异性	Detects human SOX17 in direct ELISAs. In direct ELISAs, this antibody does not cross-react with recombinant human SOX2, 3, 7, or 10.
使用方法	Immunocytochemistry: 8-25 µg/mL
来源	Reconstitute at 0.5 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	64321 (Human)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. PI3K/mTORC2 regulates TGF-beta/Activin signalling by modulating Smad2/3 activity via linker phosphorylation. Authors: Yu J, Ramasamy T, Murphy N, Holt M, Czapiewski R, Wei S, Cui W Nat Commun, 2015;6(0):7212. Species: Human Sample Type: Cell Lysates Application: WB Intrapatient variations in type 1 diabetes-specific iPS cell differentiation into insulin-producing cells. Authors: Thatava T, Kudva Y, Edukulla R, Squillace K, De Lamo J, Khan Y, Sakuma T, Ohmine S, Terzic A, Ikeda Y Mol Ther, 2013;21(1):228-39. Species: Human Sample Type: whole cells Application: Flow FGF signaling via MAPK is required early and improves Activin A-induced definitive endoderm formation from human embryonic stem cells. Authors: Sui L, Mfopou J, Geens M, Sermon K, Bouwens L Biochem Biophys Res Commun, 2012;426(3):380-5. Species: Human Sample Type: Whole Cells Application: ICC New cell lines from mouse epiblast share defining features with human embryonic stem cells. Authors: Tesar PJ, Chenoweth JG, Brook FA, Davies TJ, Evans EP, Mack DL, Gardner RL, McKay RD Nature, 2007;448(7150):196-9. Species: Mouse Sample Type: Whole Cells Application: ICC Conditional gene expression in human embryonic stem cells. Authors: Vallier L, Alexander M, Pedersen R Stem Cells, 2007;25(6):1490-7. Species: Human Sample Type: Whole Cells Application: ICC Neurogenic effect of vascular endothelial growth factor during germ layer formation of human embryonic stem cells. Authors: Kim BK, Kim SE, Shim JH, Woo DH, Gil JE, Kim SK, Kim JH FEBS Lett., 2006;580(25):5869-74. Species: Human Sample Type: Whole Cells Application: ICC
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	E. coli-derived recombinant human SOX17 Asp177-Val414 Accession # Q9H6I2
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.5 mg/mL in sterile PBS.
背景	SOX17 is a member of the SOX family of transcription factors that bind DNA via a high mobility group (HMG) domain. SOX17 is suggested to play an important role in endoderm development (1, 2).
运输条件	Blue Ice
存放说明	4℃
参考文献	Kanai-Azuma, M. et al. (2002) Development 129:2367. Katoh, M. et al. (2002) Int. J. Mol. Med. 9:153.

参考图片

SOX17 in B16 Mouse Cell Line. SOX17 was detected in immersion fixed B16 mouse melanoma cell line using Mouse Anti-Human SOX17 Monoclonal Antibody (Catalog # MAB1924) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (yellow, upper panel; Catalog # NL007) and counterstained with DAPI (blue, lower panel). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.