Human CCL2/MCP-1 MAb (Clone 23002) (25 UG)【科瑞奥博】

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Human CCL2/MCP-1 MAb (Clone 23002) (25 UG)

货号： MAB2791-SP 基本售价： 1467.3 元规格： -

产品信息

概述
货号	MAB2791-SP
别名	MCAF; MCP-1
反应种属	Human
应用	Immunohistochemistry(8-25 µg/mL)
目标/特异性	Detects human CCL2/JE/MCP-1 in ELISAs and Western blots. In ELISAs, does not cross-react with recombinant human CCL1, 3, 4, 5,7, 8, 11, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, recombinant mouseCCL1, 2, 3, 4, 5, 6, 7, 9/10/MIP-1 gamma, 11, 12, 17, 19, 20, 21, 22, 24, 25, orrecombinant rat CCL20.
使用方法	Immunohistochemistry: 8-25 µg/mL
来源	Reconstitute at 0.5 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	6347 (Human); 20296 (Mouse); 24770 (Rat); 403981 (Canine)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis. Authors: Bonapace L, Coissieux M, Wyckoff J, Mertz K, Varga Z, Junt T, Bentires-Alj M Nature, 2015;515(7525):130-3. Species: Human Sample Type: Whole Tissue Application: IHC Paraffin-embedded Exploring human testicular peritubular cells: identification of secretory products and regulation by tumor necrosis factor-alpha. Authors: Schell C, Albrecht M, Mayer C, Schwarzer JU, Frungieri MB, Mayerhofer A Endocrinology, 2008;149(4):1678-86. Species: Human Sample Type: Whole Cells Application: ICC Altered levels of CC chemokines during pulmonary CMV predict BOS and mortality post-lung transplantation. Authors: Weigt SS, Elashoff RM, Keane MP, Strieter RM, Gomperts BN, Xue YY, Ardehali A, Gregson AL, Kubak B, Fishbein MC, Saggar R, Ross DJ, Lynch JP, Zisman DA, Belperio JA Am. J. Transplant., 2008;8(7):1512-22. Species: Human Sample Type: Whole Tissue Application: IHC Paraffin-embedded The monocyte chemoattractant protein-1/cognate CC chemokine receptor 2 system affects cell motility in cultured human podocytes. Authors: Burt D, Salvidio G, Tarabra E, Barutta F, Pinach S, Dentelli P, Camussi G, Perin PC, Gruden G Am. J. Pathol., 2007;171(6):1789-99. Species: Human Sample Type: Whole Cells Application: ICC Invasive chronic inflammatory monocyte phenotype in subjects with high HIV-1 viral load. Authors: Pulliam L, Sun B, Rempel H J. Neuroimmunol., 2004;157(1):93-8. Species: Human Sample Type: Whole Cells Application: ICC
纯化方式	Protein A or G purified from ascites
免疫原	E. coli-derived recombinant human CCL2/MCP-1 Gln24-Thr99 Accession # P13500
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.5 mg/mL in sterile PBS.
背景	MCP-1 is a beta -chemokine that has been designated CCL2. It is produced bya variety of cell types and is chemotactic for monocytes.
运输条件	Blue Ice
存放说明	4℃
参考文献	CC Chemokines and Receptors Chemokines and Receptors Chemokines and Receptors in Allergy and Asthma Chemokines and Receptors in Angiogenesis gamma delta T Cells HIF Transcription Factors ICC / IHC Images: CCL2/JE/MCP-1 Inflammatory Mediators Macrophage Activation Markers Neuroinflammation

参考图片

CCL2/JE/MCP‑1 in Human Breast Cancer Tissue. CCL2/JE/MCP‑1 was detected in immersion fixed paraffin-embedded sections of human breast cancer tissue using 25 µg/mL Mouse Anti-Human CCL2/JE/MCP‑1 Monoclonal Antibody (Catalog # MAB2791) overnight at 4 °C. Tissue was stained with the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.