Mouse C1q R1/CD93 MAb (Clone 223437) (25 UG)【科瑞奥博】

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Mouse C1q R1/CD93 MAb (Clone 223437) (25 UG)

货号： MAB1696-SP 基本售价： 1467.3 元规格： -

产品信息

概述
货号	MAB1696-SP
别名	AA4 Antigen; C1q receptor 1; C1q Rp; C1q/MBL/SPA receptor; C1qR(P); C1qRp; CD93 antigenC1qR; CD93 molecule; CD93; CDw93C1QR1; Collectin Receptor; Complement component 1 q subcomponent receptor 1; complement component 1, q subcomponent, receptor 1; complement component C1q receptor; dJ737E23.1; ECSM3; Ly68; Matrix-remodeling-associated protein 4; matrix-remodelling associated 4; MXRA4
全称	Complement Component C1q Receptor
反应种属	Mouse
应用	Flow Cytometry(2.5 µg/10⁶cells) Immunocytochemistry(8-25 µg/mL)
目标/特异性	Detects mouse C1q R1/CD93 in direct ELISAs.
使用方法	Flow Cytometry: 2.5 µg/10⁶cells Immunocytochemistry: 8-25 µg/mL
来源	Reconstitute at 0.5 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	22918 (Human); 17064 (Mouse); 84398 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Membrane-associated CD93 regulates leukocyte migration and C1q-hemolytic activity during murine peritonitis. Authors: Greenlee-Wacker MC, Briseno C, Galvan M, Moriel G, Velazquez P, Bohlson SS J. Immunol., 2011;187(6):3353-61. Species: Mouse Sample Type: Peritoneal Lavage Application: ELISA Development
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Mouse myeloma cell line NS0-derived recombinant mouse C1q R1/CD93 Ala23-Asn572 Accession # O89103
生物活性	Mouse
标记	Unconjugated
溶解方法	Reconstitute at 0.5 mg/mL in sterile PBS.
背景	Complement component 1, q subcomponent receptor (C1q R1), also known as C1q Rp, Collectin receptor and AA4 antigen in rodents, mediates enhanced phagocytosis by monocytes and macrophages upon interaction with soluble defense collagens including C1q, MBL (mannose-binding lectin) and SP-A (pulmonary surfactant protein A) (1, 2). It is a type I transmembrane glycoprotein expressed on endothelial cells, hematopoietic progenitor cells, platelets and cells of myeloid origin. C1q R1 has also been identified as a stem cell marker (3, 4).
运输条件	Blue Ice
存放说明	4℃
参考文献	Kim, T.S. et al. (2000) Mol. Immunol. 37:377. Dean, Y.D. et al. (2001) Eur. J. Immunol. 31:1370. Petrenko, O. et al. (1999) Immunity 10:691. Danet, G.H. et al. (2002) Proc. Natl. Acad. Sci. USA 99:1044.

参考图片

Detection of C1q R1/CD93 in M1 Mouse Cell Line by Flow Cytometry. M1 mouse myeloid leukemia cell line was stained with Mouse C1q R1/CD93 Monoclonal Antibody (Catalog # MAB1696, filled histogram) or isotype control antibody (Catalog # MAB0061, open histogram), followed by Allophycocyanin-conjugated Anti-Rat IgG F(ab)₂ Secondary Antibody (Catalog # F0113).