货号 | MAB2145-SP |
别名 | Bonzo; BONZOG-protein coupled receptor bonzo; CD186 antigen; CD186; CDw186; chemokine (C-X-C motif) receptor 6; C-X-C chemokine receptor type 6; CXCR6; CXC-R6; CXCR-6; G protein-coupled receptor; STRL33; STRL33G-protein coupled receptor STRL33; TYMSTRCD186 |
反应种属 | Mouse |
应用 | Flow Cytometry(0.25 µg/106cells) |
目标/特异性 | Stains mouse CXCR6-transfected cells but not irrelevant transfectants. |
使用方法 | Flow Cytometry: 0.25 µg/106cells |
来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 10663 (Human); 80901 (Mouse); 100124593 (Rat) |
应用文献 | |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. The chemokine CXCL16 induces migration and invasion of glial precursor cells via its receptor CXCR6. | |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | CHO Chinese hamster ovary cell line transfected with mouse CXCR6 Met1-Leu351 Accession # Q9EQ16 |
生物活性 | Mouse |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
背景 | CXCR6, also known as Bonzo and STRL33, is a G protein coupled chemokine receptor expressed on activated T cells and tumor-infiltrating lymphocytes. It binds soluble CXCL16 and membrane-anchored CXCL16 expressed on dendritic cells and macrophages. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
|
Detection of CXCR6 in BaF3 Mouse Cell Line Transfected with Mouse CXCR6 and eGFP by Flow Cytometry. BaF3 mouse pro-B cell line transfected with mouse CXCR6 and eGFP was stained with and either (A) Rat Anti-Mouse CXCR6 Monoclonal Antibody (Catalog # MAB2145) or (B) Rat IgG2B Isotype Control (Catalog # MAB0061) followed by Allophycocyanin-conjugated Anti-Rat IgG Secondary Antibody (Catalog # F0113). View our protocol for Staining Membrane-associated Proteins. |