Human S1P1/EDG-1 MAb (Clone 218713) (25 UG)【科瑞奥博】

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Human S1P1/EDG-1 MAb (Clone 218713) (25 UG)

货号： MAB2016-SP 基本售价： 1467.3 元规格： -

产品信息

概述
货号	MAB2016-SP
简介	Clone 218713 was used by HLDA to establish CD designation
别名	CD363 antigen; CD363; CHEDG1; D1S3362; EDG1; EDG-1; EDG1edg-1; Endothelial differentiation G-protein coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; FLJ58121; S1P receptor 1; S1P receptor Edg-1; s1p1; S1P1ECGF1; S1PR1; sphingosine 1-phosphate receptor 1; sphingosine 1-phosphate receptor EDG1; Sphingosine 1-phosphate receptor Edg-1; sphingosine-1-phosphate receptor 1
全称	Endothelial Differentiation Gene 1
反应种属	Human
应用	Flow Cytometry(0.25 µg/10⁶cells)
目标/特异性	Detects human S1P₁/EDG‑1 by flow cytometry.
使用方法	Flow Cytometry: 0.25 µg/10⁶cells
来源	Reconstitute at 0.5 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	1901 (Human); 13609 (Mouse)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Hypoxia augments outgrowth endothelial cell (OEC) sprouting and directed migration in response to sphingosine-1-phosphate (S1P). Authors: Williams P, Stilhano R, To V, Tran L, Wong K, Silva E PLoS ONE, 2015;10(4):e0123437. Species: Human Sample Type: Whole Cells Application: Flow Analysis of HLDA9 mAbs on plasmacytoid dendritic cells. Authors: Cabezon R, Sintes J, Llinas L, Benitez-Ribas D Immunol. Lett., 2011;134(2):167-73. Species: Human Sample Type: Whole Cells Application: Flow New B-cell CD molecules. Authors: Matesanz-Isabel J, Sintes J, Llinas L, de Salort J, Lazaro A, Engel P Immunol. Lett., 2011;134(2):104-12. Species: Human Sample Type: Whole Cells Application: Flow Soluble forms of VEGF receptor-1 and -2 promote vascular maturation via mural cell recruitment. Authors: Lorquet S, Berndt S, Blacher S, Gengoux E, Peulen O, Maquoi E, Noel A, Foidart JM, Munaut C, Pequeux C FASEB J., 2010;24(10):3782-95. Species: Human Sample Type: Cell Lysates Application: WB
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	NS0 mouse myeloma cell line transfected with human S1P₁/EDG‑1 Met1-Ser382 Accession # P21453
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.5 mg/mL in sterile PBS.
背景	S1P₁, also known as EDG-1, is a member of the endothelial differentiation gene family. It is a high affinity G protein-coupled receptor for the bioactive lipid, Sphingosine-1-phosphate. S1P₁ signaling regulates endothelial cell survival, cytoskeletal remodeling, chemotaxis, and angiogenesis.
运输条件	Blue Ice
存放说明	4℃
参考文献	B Cell Chemotaxis, Migration, and Adhesion Bioactive Lipid G Protein-Coupled Receptors Endothelial Cell Differentiation Markers Endothelial Cell Markers Endothelial Cell Markers and Adhesion Molecules in Angiogenesis Endothelial Progenitor and Endothelial Cell Markers ICC / IHC Images: S1P1/EDG-1 Natural Killer T (NKT) Cells Steroid Hormones and Bioactive Lipids T Cell Migration/Adhesion

参考图片

Detection of S1P₁/EDG‑1 in CHO Chinese Hamster Cell Line Transfected with Human S1P₁/EDG-1 and eGFP by Flow Cytometry. CHO Chinese hamster ovary cell line transfected with either (A) human S1P₁/EDG-1 or (B) irrelevant transfectants and eGFP were stained with Mouse Anti-Human S1P₁/EDG‑1 Monoclonal Antibody (Catalog # MAB2016) followed by Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0102B). Quadrant markers were set based on control antibody staining(Catalog # MAB0041). View our protocol for Staining Membrane-associated Proteins.