货号 | MAB1439-SP |
别名 | GDNF family receptor alpha 4; GDNF family receptor alpha-4; GDNF R alpha-4; GDNF receptor alpha-4; GDNFR-alpha-4; GFR receptor alpha 4; GFRA4; GFR-alpha-4; Persephin receptor | 全称 | Glial Cell line-derived Neurotrophic Factor Receptor alpha 4 |
反应种属 | Human |
应用 | Western Blot(1 µg/mL) |
目标/特异性 | Detects human GFR alpha ‑4/GDNF R alpha ‑4 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) GFR alpha -1, recombinant rat GFR alpha -1, rhGFR alpha -2, rhGFR alpha -3, or recombinant mouse GFR alpha -4 is observed. |
使用方法 | Western Blot: 1 µg/mL |
来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 64096 (Human); 14588 (Mouse) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human GFR alpha ‑4/GDNF R alpha ‑4 Asn24-Ser245 (Ser140Cys)(predicted) Accession # NP_071422 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
背景 | GFR alpha -4 is a member of a family of at least four cysteine-richGPI-linked cell surface proteins that function as ligand bindingsubunits for the GDNF family (GDNF, neurturin, persephin and artemin).A functional receptor complex is achieved through association with thec-Ret receptor tyrosine kinase. GFR alpha -4 preferentially binds persephin. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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