货号 | MAB15241-SP |
别名 | endoglycan; PODLX2; podocalyxin-like 2; podocalyxin-like protein 2; PODXL2 |
反应种属 | Human |
应用 | Western Blot(1 µg/mL) |
目标/特异性 | Detects human Endoglycan/PODXL2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human PODXL or recombinant mouse PODXL is observed. |
使用方法 | Western Blot: 1 µg/mL |
来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 50512 (Human); 319655 (Mouse) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human Endoglycan/PODXL2 Gly33-Thr500 Accession # Q9NZ53 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
背景 | Endoglycan, also named Podocalyxin-like 2 protein, is a type I transmembrane glycoprotein. It belongs to the CD34/Podocalyxin family of sialomucins that share structural similarity and sequence homology. It is expressed in hematopoietic precursors, endothelial cells, smooth muscle cells and leukocyte subpopulations. Endoglycan is a potential marker for hematopoietic progenitors. It also functions as an L-Selectin ligand and may be involved in the inhibition of stem cell differentiation and leukocyte-endothelial adhesion (1, 2). |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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