货号 | MAB1473-SP |
别名 | coagulation factor II (thrombin) receptor-like 2; Coagulation factor II receptor-like 2 (protease-actovated receptor 3); Coagulation factor II receptor-like 2; Coagulation Factor II; F2; PAR-3; PAR3proteinase-activated receptor 3; protease-activated receptor 3; proteinase-activated receptor-3; PT; serine protease; Thrombin receptor-like 2; Thrombin |
反应种属 | Human |
应用 | Western Blot(1 µg/mL) Immunoprecipitation(25 µg/mL) |
目标/特异性 | Detects human Pro Coagulation Factor II/Thrombin in direct ELISAs and Western blots. It recognizes only Pro Coagulation Factor II/Thrombin, not active Thrombin. In Western blots, less than 5% cross-reactivity with recombinant human (rh) Factor X, rhKallikrein 1, 3, 5, and 11 is observed. |
使用方法 | Western Blot: 1 µg/mL Immunoprecipitation: 25 µg/mL |
来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 2147 (Human) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human Pro Coagulation Factor II/Thrombin Ala44-Glu622 Accession # NP_000497 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
背景 | Pro-Coagulation Factor II, also called Prothrombin, is a plasma serine protease central to thecoagulation cascade in which it converts fibrinogen to fibrin,activates factors V, VII, VIII, XIII and forms complexes with protein Cand thrombomodulin. Pro-Coagulation Factor II is an inactive precursorof thrombin that can be activated by proteolytic removal of the proregion. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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