Human beta-Catenin MAb (Clone 196618) (25 UG)【科瑞奥博】

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Human beta-Catenin MAb (Clone 196618) (25 UG)

货号： MAB13291-SP 基本售价： 1467.3 元规格： -

产品信息

概述
货号	MAB13291-SP
别名	beta 1 (88kD); beta-catenin; catenin (cadherin-associated protein), beta 1, 88kDa; catenin beta-1; CTNNB; CTNNB1; DKFZp686D02253; FLJ25606; FLJ37923
反应种属	Human
应用	Western Blot,Immunohistochemistry,Immunocytochemistry
目标/特异性	Detects human beta -Catenin in direct ELISAs.
使用方法	Western Blot: 1 µg/mL Immunohistochemistry: 8-25 µg/mL Immunocytochemistry: 8-25 µg/mL
来源	Reconstitute at 0.5 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	1499 (Human); 12387 (Mouse); 84353 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Automated Analysis and Classification of Histological Tissue Features by Multi-Dimensional Microscopic Molecular Profiling. Authors: Riordan D, Varma S, West R, Brown P PLoS ONE, 2015;10(7):e0128975. Species: Human Sample Type: Whole Tissue Application: IHC Paraffin-embedded SULF2 overexpression positively regulates tumorigenicity of human prostate cancer cells. Authors: Vicente C, Lima M, Nader H, Toma L J Exp Clin Cancer Res, 2015;34(0):25. Species: Human Sample Type: Whole Cells Application: Flow E-cadherin-expressing feeder cells promote neural lineage restriction of human embryonic stem cells. Authors: Moore RN, Cherry JF, Mathur V Stem Cells Dev., 2012;21(1):30-41. Species: Human Sample Type: Whole Cells Application: ICC Survivin in the human hair follicle. Authors: Botchkareva NV, Kahn M, Ahluwalia G, Shander D J. Invest. Dermatol., 2007;127(2):479-82. Species: Human Sample Type: Whole Tissue Application: IHC
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	E. coli-derived recombinant human beta -Catenin aa 2-781
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.5 mg/mL in sterile PBS.
背景	Beta-Catenin is a cadherin-associated protein that is involved in theregulation of cell adhesion. It also acts as as transcriptionalco-activator in the nucleus and is also involved the canonical Wntsignal transduction pathways.
运输条件	Blue Ice
存放说明	4℃
参考文献	Cancer Biomarkers Cancer Stem Cell Transcription Factors Cell to Cell Adhesion Disassembly During EMT Early Endodermal Lineage Markers Epithelial Cell Polarity ICC / IHC Images: beta-Catenin Mesenchymal Cells and EMT Neural Stem Cell Markers Notch Pathway Primitive Endoderm Markers Stem Cell Transcription Factor Regulators Transcription Factors and Regulators Transcriptional Co-Activators Wnt Family Wnt Flips a Dual Switch to Activate Adult Neurogenesis Wnt Intracellular Signaling

参考图片

beta ‑Catenin in SW480 Human Cell Line.

beta -Catenin was detected in immersion fixed SW480 human colorectal adenocarcinoma cell line using 10 µg/mL Mouse Anti-Human beta ‑Catenin Monoclonal Antibody (Catalog # MAB13291) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

beta ‑Catenin in Human Pancreas. beta ‑Catenin was detected in immersion fixed paraffin-embedded sections of human pancreas using Mouse Anti-Human beta ‑Catenin Monoclonal Antibody (Catalog # MAB13291) at 1.7 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). Specific staining was localized to plasma membranes. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.