Human D6 MAb (Clone 196124) (25 UG)【科瑞奥博】

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Human D6 MAb (Clone 196124) (25 UG)

货号： MAB1364-SP 基本售价： 1467.3 元规格： -

产品信息

概述
货号	MAB1364-SP
别名	ACKR2; C-C chemokine receptor D6; CCBP2; CCR10CCR9D6CC-chemokine-binding receptor JAB61; chemokine (C-C) receptor 9; chemokine binding protein 2; Chemokine receptor CCR-10; Chemokine receptor CCR-9; chemokine receptor D6; chemokine-binding protein 2; Chemokine-binding protein D6; CMKBR9; CMKBR9chemokine (C-C motif) receptor 9; hD6; MGC126678; MGC138250
全称	Chemokine Binding Protein 2
反应种属	Human
应用	Flow Cytometry,CyTOF-ready
目标/特异性	Detects human CC Chemokine Receptor D6 in transfectants. Does not stain the parent cell line.
使用方法	Flow Cytometry: 2.5 µg/10⁶cells
来源	Reconstitute at 0.5 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	1238 (Human); 59289 (Mouse); 140473 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Recognition versus adaptive up-regulation and degradation of CC chemokines by the chemokine decoy receptor D6 are determined by their N-terminal sequence. Authors: Savino B, Borroni EM, Torres NM, Proost P, Struyf S, Mortier A, Mantovani A, Locati M, Bonecchi R J. Biol. Chem., 2009;284(38):26207-15. Species: Human Sample Type: Whole Cells Application: Flow Regulation of D6 chemokine scavenging activity by ligand- and Rab11-dependent surface up-regulation. Authors: Bonecchi R, Borroni EM, Anselmo A, Doni A, Savino B, Mirolo M, Fabbri M, Jala VR, Haribabu B, Mantovani A, Locati M Blood, 2008;112(3):493-503. Species: Human Sample Type: Whole Cells Application: Flow Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6. Authors: Martinez de la Torre Y, Buracchi C, Borroni EM, Dupor J, Bonecchi R, Nebuloni M, Pasqualini F, Doni A, Lauri E, Agostinis C, Bulla R, Cook DN, Haribabu B, Meroni P, Rukavina D, Vago L, Tedesco F, Vecchi A, Lira SA, Locati M, Mantovani A Proc. Natl. Acad. Sci. U.S.A., 2007;104(7):2319-24. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	RBL-1 rat basophilic leukemia cell line transfected with human CC Chemokine Receptor D6 Met1-Ala384 Accession # O00590
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.5 mg/mL in sterile PBS.
背景	D6 is a seven transmembrane receptor that appears to bind to most beta chemokines. D6 expression has been reported on endothelial cells lining afferent lymphatics, placenta and a number of primitive erythromyeloid cell lines.
运输条件	Blue Ice
存放说明	4℃
参考文献	CC Chemokines and Receptors Chemokine Receptors Chemokines and Receptors in Angiogenesis Endothelial Cell Markers Endothelial Cell Markers and Adhesion Molecules in Angiogenesis

参考图片

Detection of CC Chemokine Receptor D6 in NS0 Mouse Cell Line Transfected with Human CC Chemokine Receptor D6 by Flow Cytometry. NS0 mouse myeloma cell line transfected with human CC Chemokine Receptor D6 was stained with Rat Anti-Human CC Chemokine Receptor D6 Monoclonal Antibody (Catalog # MAB1364, filled histogram) or isotype control antibody (Catalog # MAB006, open histogram), followed by Allophycocyanin-conjugated Anti-Rat IgG Secondary Antibody (Catalog # F0113).