Human alpha-Fetoprotein MAb (Clone 189506) (25 UG)【科瑞奥博】

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Human alpha-Fetoprotein MAb (Clone 189506) (25 UG)

货号： MAB1369-SP 基本售价： 1467.3 元规格： -

产品信息

概述
货号	MAB1369-SP
别名	AFP; Alpha-1-fetoprotein; alpha-fetoglobulin; alpha-fetoprotein; DSCAM2; FETA; HP; HPAFP
反应种属	Human
应用	CyTOF-reported,Immunocytochemistry,Intracellular Staining by Flow Cytometry
目标/特异性	Detects human alpha -Fetoprotein in direct ELISAs.
使用方法	Immunocytochemistry: 8-25 µg/mL Intracellular Staining by Flow Cytometry: 0.25 µg/10⁶cells
来源	Reconstitute at 0.5 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	174 (Human); 11576 (Mouse); 24177 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Frontotemporal dementia-associated N279K tau mutant disrupts subcellular vesicle trafficking and induces cellular stress in iPSC-derived neural stem cells. Authors: Wren M, Zhao J, Liu C, Murray M, Atagi Y, Davis M, Fu Y, Okano H, Ogaki K, Strongosky A, Tacik P, Rademakers R, Ross O, Dickson D, Wszolek Z, Kanekiyo T, Bu G Mol Neurodegener, 2015;10(0):46. Species: Human Sample Type: Whole Cells Application: IHC Not Specified Embryoid body formation of human amniotic fluid stem cells depends on mTOR. Authors: Valli A, Rosner M, Fuchs C, Siegel N, Bishop CE, Dolznig H, Madel U, Feichtinger W, Atala A, Hengstschlager M Oncogene, 2010;29(7):966-77. Species: Human Sample Type: Whole Cells Application: ICC Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway. Authors: Vallier L, Reynolds D, Pedersen RA Dev. Biol., 2004;275(2):403-21. Species: Human Sample Type: Whole Cells Application: ICC Central role of complement membrane attack complex in monosodium urate crystal-induced neutrophilic rabbit knee synovitis. Authors: Tramontini N, Huber C, Liu-Bryan R, Terkeltaub RA, Kilgore KS Arthritis Rheum., 2004;50(8):2633-9. Species: Human Sample Type: Whole Cells Application: ICC
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Human umbilical cord serum-derived alpha -Fetoprotein
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.5 mg/mL in sterile PBS.
背景	AFP ( alpha -Fetoprotein) is a 69-73 kDa member of the ALB/AFP/VDB family of proteins. alpha -Fetoprotein is a major plasma protein in the fetus. Its concentration is normally low in the adult except when produced by certain tumors. It is secreted by fetal liver and serves as a carrier molecule for phytoestrogens, heavy metals (Cu and Ni), estrogen and fatty acids. Mature human AFP is 591 amino acids (aa) in length. It contains three albumin domains (aa 19-210, 211-402 and 403-601), plus 15 intrachain disulfide bonds. Mature human AFP shares approximately 66% aa identity with mouse AFP.
运输条件	Blue Ice
存放说明	4℃
参考文献	Matsumura, M. et al. (2001) Hepatol. Res. 20:84 Deutsch, H.F. et al. (2000) Tumor Biol. 21:267

参考图片

alpha ‑Fetoprotein/AFP in BG01V Human Embryonic Stem Cells.
alpha ‑Fetoprotein/AFP was detected in immersion fixed BG01V human embryonic stem cells differentiated to hepatocytes using Mouse Anti-Human
alpha ‑Fetoprotein/AFP Monoclonal Antibody (Catalog # MAB1369) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. View our protocol for Fluorescent ICC Staining of Cells on Coverslips.