| 货号 | MAB2411-SP |
| 别名 | AAT3; EC 2.7.11; EC 2.7.11.30; FAA3; HNPCC6; LDS1B; LDS2B; MFS2; RIIC; TAAD2; tbetaR-II; TGF-beta receptor type II; TGF-beta receptor type IIB; TGF-beta receptor type-2; TGF-beta type II receptor; TGFbeta-RII; TGFBR2; TGFR-2; transforming growth factor beta receptor type IIC; transforming growth factor, beta receptor II (70/80kDa) isoform 1; transforming growth factor, beta receptor II (70/80kDa) isoform 2; transforming growth factor, beta receptor II (70/80kDa); transforming growth factor, beta receptor II (70-80kD); Transforming growth factor-beta receptor type II | 全称 | Transforming Growth Factor beta Receptor II |
| 反应种属 | Human |
| 应用 | Western Blot |
| 目标/特异性 | Detects human TGF-beta RII and TGF-beta RIIb in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross-react with recombinant human TGF-beta RIII, recombinant mouse (rm) TGF-beta RII, or rmTGF-beta RI. |
| 使用方法 | Western Blot: 1 µg/mL |
| 来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 7048 (Human); 21813 (Mouse) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Coordinated functions of E-cadherin and transforming growth factor beta receptor II in vitro and in vivo. | |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human TGF‑ beta RII isoform 2 Thr23-Asp184 Accession # NP_001020018 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | TGF-beta RII is a membrane-bound serine/threonine kinase. Upon ligandbinding, TGF-beta RII interacts with TGF-beta RI to form the heteromericsignaling complex that transduces TGF-beta signals. A splice variant ofthe type II receptor, TGF-beta RIIb, containing a 25 amino acid residueinsertion near the N-terminus of the mature protein has also beendescribed. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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