货号 | MAB2350-SP |
别名 | ACKR5; C-C chemokine receptor-like 2; CCR11; CCR6; CCRL2; chemokine (C-C motif) receptor-like 2; Chemokine receptor CCR11; Chemokine receptor X; CKRX; CKRXMGC116710; CRAM; CRAM-A; CRAM-B; FLJ55815; HCR; HCRMGC34104; Putative MCP-1 chemokine receptor | 全称 | CC Chemokine Receptor-like 2 |
反应种属 | Human |
应用 | Flow Cytometry,CyTOF-ready |
目标/特异性 | Detects human CCRL2/CRAM‑A/B. Stains human HCR-transfected cells but not irrelevant transfectants. It detects both the CRAM-A and CRAM-B isoforms. |
使用方法 | Flow Cytometry: 2.5 µg/106cells |
来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 9034 (Human) |
应用文献 | |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Expression, Regulation, and Function of Atypical Chemerin Receptor CCRL2 on Endothelial Cells. | |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | NS0 mouse myeloma cell line transfected with human CCRL2/CRAM‑A/B Met1-Val356 (Val180Met) Accession # NP_001124382 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
背景 | HCR, also known as CRAM-A, CRAM-B, CKRX and CCRL2, is a seven-transmembrane G-protein linked receptor that shares homology with other human chemokine receptors. Two isoforms were reported and designated CRAM-A and CRAM-B (1) that differ at their N-termini by the inclusion of an additional 12 amino acids on CRAM-A. HCR/CRAM is expressed at varying levels on a variety of peripheral blood cells including monocytes, neutrophils and T cells (2, 3). |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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