Human CCR9 MAb (Clone 112509) (25 UG)【科瑞奥博】

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Human CCR9 MAb (Clone 112509) (25 UG)

货号： MAB179-SP 基本售价： 1467.3 元规格： -

产品信息

概述
货号	MAB179-SP
简介	Clone 112509 was used by HLDA to establish CD designation
别名	C-C chemokine receptor type 9; C-C CKR-9; CC-CKR-9; CCR9; CCR-9; CD199; CDw199 antigen; CDw199; chemokine (C-C motif) receptor 9; G protein-coupled receptor 28; GPR28; GPR-9-6G-protein coupled receptor 28
反应种属	Human
应用	Flow Cytometry,Immunohistochemistry,CyTOF-ready,Immunocytochemistry
目标/特异性	Specifically stains human CCR9 transfectants and MOLT-4 cells. It does not react with the parental BaF3 cells or human CCR7-transfected BaF3 cells.
使用方法	Flow Cytometry: 2.5 µg/10⁶cells Immunohistochemistry: 8-25 µg/mL Immunocytochemistry: 15-25 µg/mL
来源	Reconstitute at 0.5 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	10803 (Human); 12769 (Mouse); 282832 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. CCL25 mediates migration, invasion and matrix metalloproteinase expression by breast cancer cells in a CCR9-dependent fashion. Authors: Johnson-Holiday C, Singh R, Johnson E Int. J. Oncol., 2011;38(5):1279-85. Species: Human Sample Type: Whole Cells Application: Neut Distribution, persistence, and efficacy of adoptively transferred central and effector memory-derived autologous Simian Immunodeficiency Virus-specific CD8(+) T cell clones in rhesus macaques during acute infection. Authors: Minang JT, Trivett MT, Bolton DL, Trubey CM, Estes JD, Li Y, Smedley J, Pung R, Rosati M, Jalah R, Pavlakis GN, Felber BK, Piatak M, Roederer M, Lifson JD, Ott DE, Ohlen C J. Immunol., 2010;184(1):315-26. Species: Primate - Macaca mulatta (Rhesus monkey) Sample Type: Whole Cells Application: Flow Trafficking, persistence, and activation state of adoptively transferred allogeneic and autologous Simian Immunodeficiency Virus-specific CD8(+) T cell clones during acute and chronic infection of rhesus macaques. Authors: Bolton DL, Minang JT, Trivett MT, Song K, Tuscher JJ, Li Y, Piatak M, OConnor D, Lifson JD, Roederer M, Ohlen C J. Immunol., 2010;184(1):303-14. Species: Primate - Macaca mulatta (Rhesus monkey) Sample Type: Whole Cells Application: Flow Down-modulation of CXCR3 surface expression and function in CD8+ T cells from cutaneous T cell lymphoma patients. Authors: Winter D, Moser J, Kriehuber E, Wiesner C, Knobler R, Trautinger F, Bombosi P, Stingl G, Petzelbauer P, Rot A, Maurer D J. Immunol., 2007;179(6):4272-82. Species: Human Sample Type: Whole Cells Application: Flow The monoclonal antibody CHO-131 identifies a subset of cutaneous lymphocyte-associated antigen T cells enriched in P-selectin-binding cells. Authors: Ni Z, Campbell JJ, Niehans G, Walcheck B J. Immunol., 2006;177(7):4742-8. Species: Human Sample Type: Whole Cells Application: Flow Possible link between unique chemokine and homing receptor expression at diagnosis and relapse location in a patient with childhood T-ALL. Authors: Annels NE, Willemze AJ, van der Velden VH, Faaij CM, van Wering E, Sie-Go DM, Egeler RM, van Tol MJ, RÃƒÂ©vÃƒÂ©sz T Blood, 2003;103(7):2806-8. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	BaF3 mouse pro-B cell line transfected with human CCR9 Met1-Leu369 Accession # P51686
生物活性	Human
标记	Unconjugated
溶解方法	Reconstitute at 0.5 mg/mL in sterile PBS.
背景	CCR9 is a G protein-linked seven transmembrane domain cytokine receptor. CCR9 serves as a receptor for CCL25/TECK. It is expressed on mature and immature thymocytes and some peripheral T and B cells.
运输条件	Blue Ice
存放说明	4℃
参考文献	Cancer Biomarkers CC Chemokines and Receptors Chemokine Receptors Chemokines and Receptors in Angiogenesis Human CD Marker Products T Cell Migration/Adhesion Thymocytes

参考图片

CCR9 in MOLT‑4 Human Cell Line. CCR9 was detected in immersion fixed MOLT‑4 human acute lymphoblastic leukemia cell line using Mouse Anti-Human CCR9 Monoclonal Antibody (Catalog # MAB179) at 25 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and counterstained with DAPI (blue). Specific staining was localized to plasma membranes. View our protocol for Fluorescent ICC Staining of Non-adherent Cells.