Mouse CXCR1/IL-8 RA MAb (Clone 1122A) (25 UL)【科瑞奥博】

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Mouse CXCR1/IL-8 RA MAb (Clone 1122A) (25 UL)

货号： MAB8628-SP 基本售价： 1467.3 元规格： -

产品信息

概述
货号	MAB8628-SP
简介	Recombinant Monoclonal Antibody
别名	CD128; CD181 antigen; CD181; CDw128aC-C; chemokine (C-X-C motif) receptor 1; CKR-1; CMKAR1; C-X-C chemokine receptor type 1; CXC-R1; CXCR-1; High affinity interleukin-8 receptor A; IL-8 receptor type 1; IL-8R A; IL8R1; IL8RA; IL8RAC-C-CKR-1; IL8RBA; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A
全称	Interleukin 8 Receptor A
反应种属	Mouse
应用	Flow Cytometry
目标/特异性	Detects mouse CXCR1 transfectants but not CXCR2 transfectants by flow cytometry.
使用方法	Flow Cytometry: 0.25 µg/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	3577 (Human); 227288 (Mouse); 54258 (Rat)
纯化方式	Protein A or G purified from cell culture supernatant
免疫原	Mouse CXCR1/IL‑8 RA Peptide Accession # Q810W6
生物活性	Mouse
标记	Unconjugated
背景	CXCR1, also known as IL-8 RA and CD181, is an approximately 60 kDa 7TM glycoprotein that functions as a receptor for the chemokine CXCL8/IL-8. It is expressed on neutrophils, monocytes, CD8 T cells, FoxP3+ CD4 Treg cells, mast cells, neuronal and glial cells, vascular endothelial cells, and melanoma. CXCR1 forms homodimers and heterodimers with CXCR2/IL-8 RB. It can be cleaved from neutrophils in the lungs of cystic fibrosis patients to release fragments that promote CXCL8 production from airway epithelial cells. CXCR1 mediates neutrophil activation and chemotaxis to sites of inflammation as well as angiogenesis and melanoma invasiveness. Mouse CXCR1 shares 65% and 89% amino acid sequence identity with human and rat CXCR1, respectively.
运输条件	Blue Ice
存放说明	4℃
参考文献	Cancer Stem Cell Markers Chemokine Receptors Chemokines and Receptors in Allergy and Asthma Chemokines and Receptors in Angiogenesis CXC Chemokines and Receptors Dendritic Cells: A New Immunotherapy? Human CD Marker Products Macrophage Activation Markers Megakaryocytes Mini-review: Multiple Sclerosis: Immune Cell Access to the Central Nervous System Monocyte Markers Neuroinflammation Neutrophils T Cell Migration/Adhesion

参考图片

Detection of CXCR1/IL‑8 RA in HEK293 Human Cell Line Transfected with Mouse CXCR1/IL‑8 RA and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with either (A) mouse CXCR1/IL‑8 RA or (B) mouse
CXCR2/IL-8 RB and eGFP was stained with Rabbit Anti-Mouse CXCR1/IL‑8 RA Monoclonal Antibody (Catalog # MAB8628). Quadrant markers were set based on control antibody staining (Catalog # AB-105-C). View our protocol for Staining Membrane-associated Proteins.