概述| 货号 | MAB912-SP |
| 别名 | CLMF2; IL12B; IL-12B; NKSF2 |
全称 | Interleukin 12/Interleukin 23 p40 | | 反应种属 | Porcine |
| 应用 | Western Blot |
| 目标/特异性 | Detects porcine IL-12/IL-23 p40 in direct ELISAs and Western blots. In Western blots (under reducing conditions), porcine IL-12/IL-23 p40 will detect the p40 subunit, but not the p35 subunit. In Western blots, less than 10% cross-reactivity with recombinant mouse IL‑12 and recombinant human IL-12 is observed. |
| 使用方法 | Western Blot: 1 µg/mL
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| 来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 3593 (Human); 16160 (Mouse); 64546 (Rat); 403976 (Canine); 493741 (Feline) |
| 纯化方式 | Protein A or G purified from ascites |
| 免疫原 | Chinese hamster ovary cell line CHO-derived recombinant porcine IL‑12 p35/p40 heterodimer |
| 生物活性 | Porcine |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | IL-12 p70 is a heterodimeric cytokine composed of one 35 kDa and one 40kDa subunit. The 40 kDa subunit also occurs in IL-23. IL-12 is producedby macrophages and B lymphocytes and has multiple effects on T cellsand natural killer (NK) cells. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Cytokines and Receptors in Allergy and Asthma
- Cytokines and Receptors in Angiogenesis
- gamma delta T Cells
- IL-10 and IL-12 Influence in Dendritic Cell Maturation
- IL-12 Family
- IL-12: Cell Protection from UVB
- Th1 Cells
- Th17 Cells
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