Human Brachyury Monoclonal Ab (Clone 1161B) (25 UL)【科瑞奥博】

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Human Brachyury Monoclonal Ab (Clone 1161B) (25 UL)

货号： MAB20851-SP 基本售价： 1467.3 元规格： -

产品信息

概述
货号	MAB20851-SP
简介	Recombinant Monoclonal Antibody
别名	brachyury protein; MGC104817; Protein T; T brachyury (mouse) homolog; T brachyury homolog; T, brachyury homolog (mouse); TF; TFT
反应种属	Human
应用	Immunocytochemistry
目标/特异性	Detects human Brachyury in direct ELISAs.
使用方法	Immunocytochemistry: 1:25-1:75 dilution
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	6862 (Human)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Combined PDGFR and HDAC Inhibition Overcomes PTEN Disruption in Chordoma. Authors: Lee D, Zhang Y, Kassam A, Park M, Gardner P, Prevedello D, Henry S, Horbinski C, Beumer J, Tawbi H, Williams B, Shaffrey M, Egorin M, Abounader R, Park D PLoS ONE, 2015;10(8):e0134426. Species: Human Sample Type: Cell Lysates Application: WB
纯化方式	Protein A or G purified from cell culture supernatant
免疫原	E. coli-derived recombinant human Brachyury Met230-Met435 Accession # O15178
生物活性	Human
标记	Unconjugated
背景	Brachyury is a 435 aa T-box family transcription factor. Human Brachyury shares 90% and 91% aa identity with mouse and rat Brachyury, respectively. It is required in the early determination and differentiation of mesoderm. Additionally, expression of Brachyury has been shown to be upregulated in a number of cancers, and in some cases, correlates with increased aggressiveness.
运输条件	Blue Ice
存放说明	4℃
参考文献	Cancer Stem Cell Transcription Factors Early Mesodermal Lineage Markers Hemangioblast Transcription Factors Hemangioblasts ICC / IHC Images: Brachyury Pluripotent Stem Cell Transcription Factors Transcription Factors and Regulators

参考图片

Brachyury in BG01V Human Embryonic Stem Cells. Brachyury was detected in immersion fixed BG01V human embryonic stem cells differentiated into mesoderm using Rabbit Anti-Human Brachyury Monoclonal Antibody (Catalog # MAB20851) at a 1:50 dilution for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Rabbit IgG Secondary Antibody (red; Catalog # NL004) and counterstained with DAPI (blue). Specific staining was localized to nuclei. View our protocol for Fluorescent ICC Staining of Stem Cells on Coverslips.