Mouse Bcl-2 MAb (Clone 121529) (25 UG)
货号：
MAB810-SP 基本售价：
1467.3 元 规格：
-
产品信息
概述| 货号 | MAB810-SP |
| 别名 | apoptosis regulator Bcl-2; B-cell CLL/lymphoma 2; Bcl-2 |
全称 | B Cell Lymphoma/Leukemia 2 | | 反应种属 | Mouse |
| 应用 | Western Blot |
| 目标/特异性 | Detects mouse Bcl‑2 Minus C-Terminus in Western blots. |
| 使用方法 | Western Blot: 0.5 µg/mL
|
| 来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 596 (Human); 12043 (Mouse); 24224 (Rat) |
| 应用文献 |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Bakuchiol-induced caspase-3-dependent apoptosis occurs through c-Jun NH2-terminal kinase-mediated mitochondrial translocation of Bax in rat liver myofibroblasts.
Authors: Park EJ, Zhao YZ, Kim YC, Sohn DH
Eur. J. Pharmacol., 2007;559(2):115-23.
Species: Mouse
Sample Type: Cell Lysates
Application: WB |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | E. coli-derived recombinant mouse Bcl-2 |
| 生物活性 | Mouse |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | The Bcl-2 family of proteins plays a crucial role in the regulation ofcell death in many eukaryotic systems. Bcl-2 is a 26 kD proteinassociated with cell survival. Over-expression of Bcl-2 has been shownto promote cell survival by suppressing apoptosis in a number of cells.The ratio of Bcl-2 to other Bcl-2 family members and subcellularlocalization are believed to modulate the apoptotic process. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Acute Lymphoblastic Leukemia
- Apoptosis: Mitochondria Accused of Murder
- Autophagy
- Bax Relocates from the Cytosol to Mitochondria to Trigger Apoptosis
- Bcl-2 Proteins and Regulators
- Cancer Biomarkers
- Common gamma Chain Receptor Family
- Cytokine-related Mechanisms of Apoptosis
- DNA Damage and Repair
- ICC / IHC Images: Bcl-2
- Lymphoma
- Mini-review: Apoptosis I
- Notch Pathway
- ROS and Stress Resistance
- VEGF Family
|
参考图片Detection of Mouse Bcl‑2 by Western Blot. Western blot shows lysates of CTLL-2 mouse cytotoxic T cell line. PVDF membrane was probed with 0.5 µg/mL Rat Anti-Mouse Bcl‑2 Minus C-Terminus Monoclonal Antibody (Catalog # MAB810) followed by HRP-conjugated Anti-Rat IgG Secondary Antibody (Catalog # HAF005). For additional reference, Recombinant Human Bcl‑2 Minus C-Terminus (Catalog # 827-BC) (2 ng) was included. A specific band for Bcl-2 was detected at approximately 26 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 4. |
