Human/Mouse Bax MAb (Clone 127602) (25 UG)
货号：
MAB883-SP 基本售价：
1467.3 元 规格：
-
产品信息
概述| 货号 | MAB883-SP |
| 别名 | apoptosis regulator BAX; BCL2-associated X protein; Bcl2-L-4; BCL2L4bcl2-L-4; Bcl-2-like protein 4 |
全称 | Bcl Associated X Protein | | 反应种属 | Human/Mouse |
| 应用 | Western Blot |
| 目标/特异性 | Detects human and mouse full-length Bax in Western blots. |
| 使用方法 | Western Blot: 1.0-2.0 µg/mL
|
| 来源 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 581 (Human); 12028 (Mouse); 24887 (Rat) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Bax minus the carboxyl terminal |
| 生物活性 | Human, Mouse |
| 标记 | Unconjugated |
| 背景 | Bax belongs to the Bcl2 protein family. It forms homodimers and heterodimers with Bcl2 and functions as an apoptotic activator. Bax interacts with the mitochondrial voltage dependent anion channel and promotes the release of cytochrome c. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Bax Relocates from the Cytosol to Mitochondria to Trigger Apoptosis
- Bcl-2 Proteins and Regulators
- Cell Structure and Signaling Molecules
- ICC / IHC Images: Bax
|
参考图片Detection of Human/Mouse Bax Minus C-Terminus by Western Blot. Western blot shows lysates of L‑929 mouse fibroblast cell line and THP‑1 human acute monocytic leukemia cell line. PVDF membrane was probed with 1.0-2.0 µg/mL of Human/Mouse Bax Minus C-Terminus Monoclonal Antibody (Catalog # MAB883) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for Bax Minus C-Terminus at approximately 21 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 4. |
