货号 | MAB5891-SP |
别名 | CD122 antigen; CD122; high affinity IL-2 receptor beta subunit; High affinity IL-2 receptor subunit beta; IL-15 R beta; IL-2 receptor subunit beta; IL-2R subunit beta; IL2RB; IL-2RB; interleukin 15 receptor, beta; interleukin 2 receptor, beta; interleukin-2 receptor subunit beta; P70-75; p75 | 全称 | Interleukin 2 Receptor beta |
反应种属 | Mouse |
应用 | Flow Cytometry,CyTOF-ready |
目标/特异性 | Detects mouse IL-2 R beta in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL‑2 R alpha, rhIL-2 R beta, recombinant mouse (rm) IL-2 R gamma, rhIL-15 R alpha, or rmIL-21 R is observed. |
使用方法 | Flow Cytometry: 2.5 µg/106cells |
来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 3560 (Human); 16185 (Mouse) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse IL-2 R beta Ala27-Glu240 Accession # P16297 |
生物活性 | Mouse |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
背景 | IL‑2 R beta (IL-2 Receptor beta ; designated CD122) is a type I transmembrane protein that associates with IL-2 R alpha and the common gamma chain to form a high affinity heterotrimeric receptor complex for IL-2. IL‑2 R beta and the common gamma chain can also associate with IL-15 R alpha. IL-2 R beta is expressed by T, B, NK cells and monocyte/macrophages. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of IL‑2 R beta in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with anti-mouse Integrin alpha 2/CD49b APC‑conjugated antibody and either (A) Rat Anti-Mouse IL‑2 R beta Monoclonal Antibody (Catalog # MAB5891) or (B) Rat IgG2A Isotype Control (Catalog # MAB006) followed by Phycoerythrin-conjugated Anti-Rat IgG Secondary Antibody (Catalog # F0105B). |