| 货号 | 48866S |
| 同种亚型 | Rabbit IgG |
| 反应种属 | M |
| 来源宿主 | Rabbit IgG |
| 应用 | F |
| 目标/特异性 | iNOS (D6B6S) Rabbit mAb (Alexa Fluor®647 Conjugate) recognizes endogenous levels of total iNOS protein. This antibody does not cross-react with other NOS proteins. |
| 使用方法 | F(1:50) |
| 供应商 | CST |
| 灵敏度 | Endogenous |
| 背景 | Nitric Oxide Synthase (NOS) catalyzes the formation of nitric oxide (NO) and citruline from L-arginine, oxygen and cofactors. Three family members have been characterized: neuronal NOS (nNOS), which is found primarily in neuronal tissue; inducible NOS (iNOS), which is induced by interferon gamma and lipopolysaccharides in the kidney and cardiovascular system; and endothelial NOS (eNOS), which is expressed in blood vessels (1). NO is a messenger molecule with diverse functions throughout the body including the maintenance of vascular integrity, homeostasis, synaptic plasticity, long-term potentiation, learning, and memory (2,3). |
| 运输条件 | 0.75 |
| 存放说明 | 4C |
| 参考文献 | 1 . Tsutsui, M. (2004) J Atheroscler Thromb 11, 41-48. 2 . Son, H. et al. (1996) Cell 87, 1015-23. 3 . Hawkins, R.D. (1996) Neuron 16, 465-467. |
Flow cytometric analysis of Raw309.CR.1 cells untreated (blue) or #14011 Lipopolysaccharides (LPS) treated (green) using iNOS (D6B6S) Rabbit mAb (Alexa Fluor®647 Conjugate). |
