VDAC (D73D12) Rabbit mAb (HRP Conjugate)
货号：
12454S 基本售价：
4060.0 元 规格：
-
产品信息
概述| 货号 | 12454S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | VDAC (D73D12) Rabbit mAb (HRP Conjugate) detects endogenous levels of total VDAC protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 标记 | HRP |
| 背景 | Voltage-dependent anion channel (VDAC), ubiquitously expressed and located in the outer mitochondrial membrane, is generally thought to be the primary means by which metabolites diffuse in and out of the mitochondria (1). In addition, this channel plays a role in apoptotic signaling. The change in mitochondrial permeability characteristic of apoptosis is mediated by Bcl-2 family proteins, which bind to VDAC, altering the channel kinetics (2). Homodimerization of VDAC may be a mechanism for changing mitochondrial permeability and supporting release of cytochrome c (3). In mammalian cells, there are three VDAC isoforms, VDAC1, which is the most widely expressed isoform, as well as VDAC2 and VDAC3 (4,5). |
| 存放说明 | -20C |
| 计算分子量 | 32 |
参考图片Western blot analysis of extracts from COS-7 and HeLa cells using VDAC (D73D12) Rabbit mAb (HRP Conjugate). 使用VDAC (D73D12) Rabbit mAb (HRP Conjugate)兔单抗对COS-7和HeLa细胞提取物进行western blot分析。 |
